ArticleScientific reports2016
Elucidating a molecular mechanism that the deterioration of porcine meat quality responds to increased cortisol based on transcriptome sequencing.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Supplementing Lactobacillus brevis metabolite modifies carcass performances, characteristics of meat, taste-related compounds and fatty acid profiles of heat stressed Chikso cattle.Animal bioscience · 2026Article
- Integrating Transcriptomics and Metabolomics to Unravel the Molecular Mechanisms of Meat Quality: A Systematic Review.Foods (Basel, Switzerland) · 2026Review
- Fasting influences the muscle quality of fish during transportation by regulating the balance between energy metabolism and ammonia nitrogen stress.Journal of advanced research · 2026Article
- Depuration and Starvation Regulate Metabolism and Improve Flesh Quality of Yellow Catfish (Metabolites · 2023Article
- Identification and verification of a novel anoikis-related gene signature with prognostic significance in clear cell renal cell carcinoma.Journal of cancer research and clinical oncology · 2023Article
- Differential gene expression analysis using RNA-seq in the blood of goats exposed to transportation stress.Scientific reports · 2023Article
- RNA-Seq exploration of the influence of stress on meat quality in Spanish goats.Scientific reports · 2022Article
- Effect of Respite Time before Live Transportation on Muscle Quality of Blunt Snout (Wuchang) Bream.Foods (Basel, Switzerland) · 2022Article
- Association of Serum Glucose, Serotonin, Aspartate Aminotransferase, and Calcium Levels with Meat Quality and Palatability Characteristics of BroilerAnimals : an open access journal from MDPI · 2022Article
- Glucocorticoid Regulates the Synthesis of Porcine Muscle Protein through mInternational journal of molecular sciences · 2022Article
- Glucocorticoid Receptor Alpha Targets SLC2A4 to Regulate Protein Synthesis and Breakdown in Porcine Skeletal Muscle Cells.Biomolecules · 2021Article
- Genetic control of longissimus dorsi muscle gene expression variation and joint analysis with phenotypic quantitative trait loci in pigs.BMC genomics · 2019Article
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Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Stress response is tightly linked to meat quality. The current understanding of the intrinsic mechanism of meat deterioration under stress is limited. Here, male piglets were randomly assigned to cortisol and control groups. Our results showed that when serum cortisol level was significantly increased, the meat color at 1 h postmortem, muscle bundle ratio, apoptosis rate, and gene expression levels of calcium channel and cell apoptosis including SERCA1, IP3R1, BAX, Bcl-2, and Caspase-3, were notably increased. However, the value of drip loss at 24 h postmortem and serum CK were significantly decreased. Additionally, a large number of differentially expressed genes (DEGs) in GC regulation mechanism were screened out using transcriptome sequencing technology. A total of 223 DEGs were found, including 80 up-regulated genes and 143 down-regulated genes. A total of 204 genes were enriched in GO terms, and 140 genes annotated into in KEGG database. Numerous genes were primarily involved in defense, inflammatory and wound responses. This study not only identifies important genes and signalling pathways that may affect the meat quality but also offers a reference for breeding and feeding management to provide consumers with better quality pork products.
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