Evidence map›Paper›PMID 27833096›Full record

ArticleExperimental & molecular medicine2016

Immunoproteasome induction is suppressed in hepatitis C virus-infected cells in a protein kinase R-dependent manner.

In Soo Oh, Kathrin Textoris-Taube, Pil Soo Sung, Wonseok Kang, Xenia Gorny, Thilo Kähne, Seon-Hui Hong, Young Joon Choi, Clemens Cammann, Michael Naumann and 6 more

Open access · goldAbstract read
In one paragraph

Article in Experimental & molecular medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. [Research progress on selective immunoproteasome inhibitors].Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 2 countries.

In Soo OhLaboratory of Immunology and Infectious Diseases, Graduate School of Medical Science and Engineering, KAIST, Daejeon, Republic of Korea.
Kathrin Textoris-TaubeInstitute for Biochemistry CCM, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Pil Soo SungLaboratory of Immunology and Infectious Diseases, Graduate School of Medical Science and Engineering, KAIST, Daejeon, Republic of Korea.
Wonseok KangLaboratory of Immunology and Infectious Diseases, Graduate School of Medical Science and Engineering, KAIST, Daejeon, Republic of Korea.
Xenia GornyInstitute for Molecular and Clinical Immunology, Medical Faculty of the Otto-von-Guericke-University Magdeburg, Magdeburg, Germany.
Thilo KähneInstitute of Experimental Internal Medicine, Medical Faculty of the Otto-von-Guericke-University, Magdeburg, Germany.
Seon-Hui HongLaboratory of Immunology and Infectious Diseases, Graduate School of Medical Science and Engineering, KAIST, Daejeon, Republic of Korea.
Young Joon ChoiLaboratory of Immunology and Infectious Diseases, Graduate School of Medical Science and Engineering, KAIST, Daejeon, Republic of Korea.
Clemens CammannInstitute for Molecular and Clinical Immunology, Medical Faculty of the Otto-von-Guericke-University Magdeburg, Magdeburg, Germany.
Michael NaumannInstitute of Experimental Internal Medicine, Medical Faculty of the Otto-von-Guericke-University, Magdeburg, Germany.
Jong Hoon KimLaboratory of Immunology and Infectious Diseases, Graduate School of Medical Science and Engineering, KAIST, Daejeon, Republic of Korea.
Su-Hyung ParkLaboratory of Translational Immunology and Vaccinology, Graduate School of Medical Science and Engineering, KAIST, Daejeon, Republic of Korea.
Ook Joon YooLaboratory of Molecular Biology, Graduate School of Medical Science and Engineering, KAIST, Daejeon, Republic of Korea.
Peter M KloetzelInstitute for Biochemistry CCM, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Ulrike SeifertInstitute for Molecular and Clinical Immunology, Medical Faculty of the Otto-von-Guericke-University Magdeburg, Magdeburg, Germany.
Eui-Cheol ShinLaboratory of Immunology and Infectious Diseases, Graduate School of Medical Science and Engineering, KAIST, Daejeon, Republic of Korea.
Korea Advanced Institute of Science and Technology · KROtto-von-Guericke University Magdeburg · DEBerlin Institute of Health at Charité - Universitätsmedizin Berlin · DECharité - Universitätsmedizin Berlin · DEFriedrich-Loeffler-Institut · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

By changing the relative abundance of generated antigenic peptides through alterations in the proteolytic activity, interferon (IFN)-γ-induced immunoproteasomes influence the outcome of CD8

Indexed as

Cell Line, TumoreIF-2 KinaseGene Expression RegulationHepacivirusHepatitis CHumansInterferon-gammaProteasome Endopeptidase ComplexRNA, MessengerEIF2AK2 protein, humaneIF-2 KinaseInterferon-gammaProteasome Endopeptidase ComplexRNA, Messenger

Identifiers

PMID27833096
PMCPMC5133375
OpenAlexW2552317700

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.