Evidence map›Paper›PMID 27832841›Full record

ReviewBiological psychiatry2017

New Concepts in Dopamine D

Nikhil M Urs, Sean M Peterson, Marc G Caron

Open access · bronzeAbstract readReview
In one paragraph

Review in Biological psychiatry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
68citing papers in PubMed, 1 pooled it
10.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

68 citing papers in PubMed, 1 synthesis or guideline pooled it, 118 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Biased Signaling in Psychedelic Action.Annual review of pharmacology and toxicology · 2026
    Review
  4. Review
  5. Lost in translation: why don't dopamine D2 antagonists cure addictions?Journal of psychiatry & neuroscience : JPN · 2026
    Article
  6. Biased Allosteric Modulation in GPCR Drug Discovery.Handbook of experimental pharmacology · 2026
    Review
  7. Review
  8. Review
  9. Review
  10. Article
  11. Article
  12. Arrestin-3 Agonism at Dopamine DBiological psychiatry · 2023
    Article
  13. Identification of a β-arrestin-biased negative allosteric modulator for the βProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  14. Review
  15. Review
  16. Review
  17. Article
  18. Review
  19. Review
  20. Article

8 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Nikhil M UrsDepartments of Cell Biology, Duke University Medical Center, Durham, North Carolina.
Sean M PetersonDepartments of Cell Biology, Duke University Medical Center, Durham, North Carolina.
Marc G CaronDepartments of Cell Biology, Duke University Medical Center, Durham, North Carolina; Medicine, Duke University Medical Center, Durham, North Carolina; Neurobiology, Duke University Medical Center, Durham, North Carolina. Electronic address: marc.caron@dm.duke.edu.
Duke Medical Center · USDuke University · USDuke University Hospital · US

Funding

Screening CoreU19MH082441 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI CARON, MARC G., ROTH, BRYAN L. · 2007 to 2016
$15.2M
Akt/GSK-3 Signaling Cascade and the Actions of DopamineR37MH073853 · NIMH · DUKE UNIVERSITY · PI CARON, MARC G. · 2011 to 2020
$6.4M
NIMH NIH HHS R37 MH073853NIMH NIH HHS U19 MH082441
6 · The paper itself

Abstract

The dopamine D

Indexed as

AnimalsAntipsychotic Agentsbeta-ArrestinsBrainCorpus StriatumDopamine AgonistsDopamine D2 Receptor AntagonistsHumansMiceRatsReceptors, Dopamine D2SchizophreniaSignal TransductionAntipsychotic Agentsbeta-ArrestinsDopamine AgonistsDopamine D2 Receptor AntagonistsReceptors, Dopamine D2AntipsychoticsArrestinDopamineFunctional selectivitySchizophreniaSystem bias

Identifiers

PMID27832841
PMCPMC5702557
OpenAlexW2532143627

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.