Evidence map›Paper›PMID 27832585›Full record

ArticleCell host & microbe2016

Tackling Difficult Staphylococcus aureus Infections: Antibodies Show the Way.

Bo Shopsin, Srini V Kaveri, Jagadeesh Bayry

Open access · bronzeAbstract readComment
PubMed Publisher
In one paragraph

Article in Cell host & microbe, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 29 citations in OpenAlex.

  1. Review
  2. Microbiota and metabolic adaptation shapebioRxiv : the preprint server for biology · 2024
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  3. Review
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  6. Observational
  7. Article
  8. Review
  9. Review
  10. COVID-19: benefits and risks of passive immunotherapeutics.Human vaccines & immunotherapeutics · 2020
    Review
  11. Review
  12. Review
  13. Article
  14. Intravenous Immunoglobulin Therapy EliminatesInternational journal of molecular sciences · 2019
    Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Bo ShopsinDepartment of Microbiology, New York University School of Medicine, New York, NY 10016, USA; Division of Infectious Diseases, Department of Medicine, New York University School of Medicine, New York, NY 10016, USA.
Srini V KaveriInstitut National de la Santé et de la Recherche Médicale Unité 1138, Paris 75006, France; Sorbonne Universités, UPMC Univ Paris 06, UMR S 1138, Paris 75006, France; Université Paris Descartes, Sorbonne Paris Cité, UMR S 1138, Paris 75006, France; Centre de Recherche des Cordeliers, Equipe - Immunopathologie et immuno-intervention thérapeutique, Paris 75006, France.
Jagadeesh BayryInstitut National de la Santé et de la Recherche Médicale Unité 1138, Paris 75006, France; Sorbonne Universités, UPMC Univ Paris 06, UMR S 1138, Paris 75006, France; Université Paris Descartes, Sorbonne Paris Cité, UMR S 1138, Paris 75006, France; Centre de Recherche des Cordeliers, Equipe - Immunopathologie et immuno-intervention thérapeutique, Paris 75006, France. Electronic address: jagadeesh.bayry@crc.jussieu.fr.
Délégation Paris 5 · FRNew York University · US

Funding

Role of precipitous virulence in invasiveness of community-acquired methicillin-rR01AI103268 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI SHOPSIN, BO, TORRES, VICTOR J. · 2013 to 2017
$2.1M
6 · The paper itself

Abstract

The recent spread of community-acquired methicillin-resistant Staphylococcus aureus (MRSA) has brought increasing concerns of heightened disease severity and persistence following invasive disease. In line with the need for new treatment paradigms, two recent reports have shown that antibody-based therapies can restrict acute S. aureus infection and persistence and improve pathological symptoms.

Indexed as

LeukocidinsMethicillin-Resistant Staphylococcus aureusBacterial ToxinsCommunity-Acquired InfectionsExotoxinsHumansStaphylococcal InfectionsStaphylococcus aureusBacterial ToxinsExotoxinsLeukocidinsantibioticImmunoglobulinintravenous immunoglobulinIVIGnecrotizing pneumoniaPanton-Valentine leukocidinphagocytesrifalogueThiomabα-hemolysin

Identifiers

PMID27832585
OpenAlexW2551657189

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.