Evidence map›Paper›PMID 27832442›Full record

ReviewCurrent rheumatology reports2016

Cannabinoids in the Management of Musculoskeletal or Rheumatic Diseases.

Mary-Ann Fitzcharles, Winfried Häuser

Registry-linked trialAbstract readReview
PubMed Publisher
In one paragraph

Review in Current rheumatology reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04298528 (A Prospective, Randomized, Double Blind Trial Comparing Dronabinol to a Placebo in the Management of Post-operative Pain in Total Joint Arthroplasty), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04298528 phase3unknown statusnot on this mapstarted 2020, after this paper: background citation

A Prospective, Randomized, Double Blind Trial Comparing Dronabinol to a Placebo in the Management of Post-operative Pain in Total Joint Arthroplasty

TypeinterventionalSponsorColorado Joint ReplacementRan2020 to 2025Enrolled460ConditionsOsteoarthritis, KneeArmsDronabinol, Placebo
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Cannabis and pain: a scoping review.Brazilian journal of anesthesiology (Elsevier)
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Mary-Ann FitzcharlesDivision of Rheumatology, McGill University Health Centre, Montréal, Quebec, Canada. mary-ann.fitzcharles@muhc.mcgill.ca.
Winfried HäuserDepartment Internal Medicine I, Klinikum Saarbrücken, Saarbrücken, Germany.
Klinikum Saarbrücken · DEMcGill University Health Centre · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The endocannabinoid system impacts pain and inflammation with potential for therapeutic effect on patients with rheumatic diseases. The current treatment options include the herbal product derived from the plant Cannabis sativa, as well as pharmaceutical preparations. The legalization of medicinal cannabis (marijuana) in many jurisdictions and widespread public advocacy has propelled an interest in use either by prescription or self-medication. In this review, we examine current evidence for efficacy and adverse effects of any cannabinoid product in rheumatic conditions. The evidence to date is scant and precludes making recommendations for the use of cannabinoid preparations in rheumatology patients. In particular, the risks of herbal cannabis in patients are not well defined. Anecdote and advocacy cannot supersede sound evidence.

Indexed as

AnalgesicsCannabinoidsHumansMusculoskeletal DiseasesRheumatic DiseasesAnalgesicsCannabinoidsCannabinoidsMarijuanaRheumatic disease

Identifiers

PMID27832442
OpenAlexW2556332421

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.