Evidence map›Paper›PMID 27832440›Full record

ArticleProbiotics and antimicrobial proteins2017

Influence of Hydrogen Peroxide, Lactic Acid, and Surfactants from Vaginal Lactobacilli on the Antibiotic Sensitivity of Opportunistic Bacteria.

Andrey Sgibnev, Elena Kremleva

Abstract read
PubMed Publisher
In one paragraph

Article in Probiotics and antimicrobial proteins, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 25 citations in OpenAlex.

  1. Review
  2. Regulatory Effects ofMicroorganisms · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Isolation and characterization ofFrontiers in microbiology · 2025
    Article
  8. Lactobacillus acidophilus VB1 co-aggregates and inhibits biofilm formation of chronic otitis media-associated pathogens.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024
    Article
  9. Article
  10. Article
  11. Frontiers in veterinary science · 2021
    Article
  12. Vaginal ProbioticFrontiers in cell and developmental biology · 2021
    Article
  13. BioMed research international · 2021
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Andrey SgibnevInstitute of Cellular and Intracellular Symbiosis, str. Pionerskaja, 11, Orenburg, Russian Federation, 460000. sgibnew72@yandex.ru.
Elena KremlevaInstitute of Cellular and Intracellular Symbiosis, str. Pionerskaja, 11, Orenburg, Russian Federation, 460000.
Institute of Cellular and Intracellular Symbiosis · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We studied as hydrogen peroxide, lactic acid, or surfactants from clinical isolates of vaginal lactobacilli and cell-free supernatants from probiotic strain LCR35 can influence on the sensitivity of opportunistic bacteria to antibiotics. We found that the most effective in increasing sensitivity to antibiotics were hydrogen peroxide and surfactants or their combination but no lactic acid. In some cases, the effect of the composition of hydrogen peroxide and surfactants was clearly higher than the sum of effects of these substances alone. With using of the supernatant of LCR35 was shown that the combination of surfactant and lactate has greater effect compared with surfactants alone. In concluding, metabolites of vaginal lactobacilli are suitable for the role of "antibiotic assistants" and it can help solve the problems the antibiotic resistance.

Indexed as

Anti-Bacterial AgentsBacteriaFemaleHumansHydrogen PeroxideLactic AcidLactobacillusSurface-Active AgentsVaginaAnti-Bacterial AgentsHydrogen PeroxideLactic AcidSurface-Active AgentsAntibiotic resistanceHydrogen peroxideLactic acidLactobacillusProbioticsSurface-active agents

Identifiers

PMID27832440
OpenAlexW2549527568

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.