Evidence map›Paper›PMID 27832399›Full record

Trial reportJournal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing2017

Ablation of atypical atrial flutters using ultra high density-activation sequence mapping.

Roger A Winkle, Ryan Moskovitz, R Hardwin Mead, Gregory Engel, Melissa H Kong, William Fleming, Rob A Patrawala

Open access · hybridAbstract readClinical Trial
In one paragraph

Trial report in Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.1field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 39 citations in OpenAlex.

  1. Substrate ablation as concomitant treatment for left atrial macroreentrant tachycardia (SLICE-LAMRT): rationale and study design.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2026
    Trial
  2. Article
  3. Article
  4. Outcome after ablation of atypical atrial flutter: Is induction a feasible approach?International journal of cardiology. Heart & vasculature · 2024
    Article
  5. Clinical impact of high-density mapping on the acute and long term outcome of atypical atrial flutter ablations.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2024
    Article
  6. Review
  7. Atypical atrial flutter catheter ablation in the era of high-density mapping.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2023
    Article
  8. Outcomes of catheter ablation of atrial tachyarrhythmia guided exclusively by activation mapping.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2023
    Article
  9. Article
  10. Clinical utility of non-contact charge density 'SuperMap' algorithm for the mapping and ablation of organized atrial arrhythmias.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2022
    Article
  11. High-density mapping with fragmentation analysis in patients with reentrant atrial tachycardias (MAP-FLURHY study).Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2022
    Article
  12. Article
  13. Article
  14. High-density versus low-density mapping in ablation of atypical atrial flutter.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2021
    Article
  15. Article
  16. Novel noncontact charge density map in the setting of post-atrial fibrillation atrial tachycardias: first experience with the Acutus SuperMap Algorithm.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2021
    Article
  17. The evolution of mapping and ablation techniques in the treatment of atrial tachycardias occurring after atrial fibrillation ablation.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2021
    Article
  18. Initial multicenter experience with a new high-density coloring module: impact for complex atrial arrhythmias interpretation.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2021
    Article
  19. Article
  20. Catheter ablation for failed surgical maze: comparison of cut and sew vs. non-cut and sew maze.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Roger A WinkleSilicon Valley Cardiology, 1950 University Avenue, Suite 160, E. Palo Alto, CA, 94303, USA. rawinkle@aol.com.
Ryan MoskovitzSt. Jude Medical, Inc., St. Paul, MD, USA.
R Hardwin MeadSilicon Valley Cardiology, 1950 University Avenue, Suite 160, E. Palo Alto, CA, 94303, USA.
Gregory EngelSilicon Valley Cardiology, 1950 University Avenue, Suite 160, E. Palo Alto, CA, 94303, USA.
Melissa H KongSilicon Valley Cardiology, 1950 University Avenue, Suite 160, E. Palo Alto, CA, 94303, USA.
William FlemingSilicon Valley Cardiology, 1950 University Avenue, Suite 160, E. Palo Alto, CA, 94303, USA.
Rob A PatrawalaSilicon Valley Cardiology, 1950 University Avenue, Suite 160, E. Palo Alto, CA, 94303, USA.
Silicon Valley University · USSequoia Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe purpose of this study was to evaluate ultra high density-activation sequence mapping (UHD-ASM) for ablating atypical atrial flutters.

methodsFor 23 patients with 31 atypical atrial flutters (AAF), we created UHD-ASM.

resultsDemographics age = 65.3 ± 8.5 years, male = 78%, left atrial size = 4.66 ± 0.64 cm, redo ablation 20/23(87%). AAF were left atrial in 30 (97%). For each AAF, 1273 ± 697 points were used for UHD-ASM. Time to create and interpret the UHD-ASM was 20 ± 11 min. For every AAF, the entire circuit was identified. Thirty (97%) were macroreentry. AAF cycle length was 267 ± 49 ms, and the circuit length was 138 ± 38 mm (range 35-187). Macroreentry atrial flutters took varied pathways, but each had an area of slow conduction (ASC) averaging 16 ± 6 mm (range 6-29) in length. Entrainment was not utilized. We targeted the ASC and ablation terminated AAF directly in 19/31 (61.3%) and altered AAF activation in 7/31 (22.6%), all of which terminated directly with additional mapping/ablation. AAF degenerated to atrial fibrillation in 2/31 (6.5%) with RF and could not be reinduced after ASC ablation. Median time from initial ablation to AAF termination was 64 s. Thus, 28/31 (90.3%) terminated with RF energy and/or could not be reinduced after ASC ablation. At 1 year of follow-up, 77% were free of atrial tachycardia or atrial flutter and 61% were free of all atrial arrhythmias.

conclusionsUsing rapidly acquired UHD-ASM, the entire AAF circuit as well as the target ASC could be identified. Most AAF were left atrial macroreentry. Ablation of the ASC or microreentry focuses directly terminated or eliminated AAF in 90.3% without the need for entrainment mapping.

Indexed as

Body Surface Potential MappingAgedAtrial FlutterCatheter AblationFemaleHumansImage EnhancementImaging, Three-DimensionalMaleMiddle AgedSurgery, Computer-AssistedTreatment OutcomeActivation mappingAtrial flutterAtrial flutter ablationAtypical atrial flutterLeft atrial flutter

Identifiers

PMID27832399
PMCPMC5325851
OpenAlexW2555563702

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.