Evidence map›Paper›PMID 27832398›Full record

ArticleInflammation2017

Berberine Attenuates Inflammation Associated with Delayed-Type Hypersensitivity via Suppressing Th1 Response and Inhibiting Apoptosis.

Zhigang Wang, Zhe Chen, Tao Chen, Tao Yi, Zhou Zheng, Hong Fan, Zebin Chen

Abstract read
PubMed Publisher
In one paragraph

Article in Inflammation, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
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  4. Review
  5. Article
  6. Berberine improves central memory formation of CD8Acta pharmaceutica Sinica. B · 2023
    Article
  7. The effectiveness of berberine on noise-induced hearing loss: a rat model.Revista da Associacao Medica Brasileira (1992) · 2022
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. The ameliorative effect of berberine and coenzyme Q10 in an ovalbumin-induced allergic rhinitis model.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2018
    Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Zhigang WangDepartment of Pathogen Biology, College of Basic Medicine, Hubei University of Chinese Medicine, Wuhan, 430065, China.
Zhe ChenDepartment of Integrated Chinese Traditional and Western Medicine, Tongji Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology, Wuhan, 430030, China.
Tao ChenDepartment of Anatomy, College of Basic Medicine, Hubei University of Chinese Medicine, Wuhan, 430065, China.
Tao YiCollege of Basic Medicine, Hubei University of Chinese Medicine, Wuhan, 430065, China.
Zhou ZhengDepartment of Anatomy, College of Basic Medicine, Hubei University of Chinese Medicine, Wuhan, 430065, China.
Hong FanDepartment of Pathogen Biology, College of Basic Medicine, Hubei University of Chinese Medicine, Wuhan, 430065, China.
Zebin ChenHubei Provincial Collaborative Innovation Center of Preventive Treatment by Acupuncture and Moxibustion, Hubei University of Chinese Medicine, 1 Huangjiahu West Road, Hongshan District, Wuhan, 430065, Hubei, China. chenzebin-hbtcm@outlook.com.
Hubei University of Chinese Medicine · CNTongji Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Berberine, one of the active alkaloids from Rhizoma Coptidis, has been indicated to have anti-inflammatory and immunosuppressive properties. The aim of this study was to determine the role of berberine on ovalbumin (OVA)-induced delayed-type hypersensitivity (DTH) and its potential mechanisms. Berberine treatment significantly reduced footpad swelling, inflammatory cells infiltration, anti-OVA IgG levels, IgE concentration in serum, and the tetramer

Indexed as

AnimalsAnti-Inflammatory AgentsApoptosisBerberineCell DifferentiationCytokinesHypersensitivity, DelayedImmunosuppressive AgentsInflammationMiceOvalbuminTh1 CellsAnti-Inflammatory AgentsBerberineCytokinesImmunosuppressive AgentsOvalbuminapoptosisberberinedelayed-type hypersensitivityinflammationTh1 response

Identifiers

PMID27832398
OpenAlexW2553710753

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.