ReviewSchmerz (Berlin, Germany)2016
[Mechanisms of chronification and potential addiction in tumor pain : Comparison with non-tumor pain - A review of the literature].
Review in Schmerz (Berlin, Germany), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 17 citations in OpenAlex.
- [Influence of health care crises on the treatment of cancer pain: a presentation using the example of the COVID-19 pandemic from the provider's perspective].Schmerz (Berlin, Germany) · 2026Article
- Correlation between mental health and pain-related impairment in patients with chronic cancer-related pain.Frontiers in psychology · 2026Article
- [Treatment of cancer-related pain-From pharmacotherapy to invasive procedures].Die Anaesthesiologie · 2025Review
- Cancer-related pain in long-term survivors of oncological diseases: results of a survey on the current care situation.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Article
- [Factors influencing analgesic use patterns in patients with chronic tumor-associated pain. : A qualitative pilot study considering different groups of medications].Schmerz (Berlin, Germany) · 2024Article
- [Tumor-associated pain].Schmerz (Berlin, Germany) · 2024Article
- [Applicability of QUIKS in conservatively treated tumor inpatients].Schmerz (Berlin, Germany) · 2022Article
- [Use of rapid-onset fentanyl preparations beyond indication : A random questionnaire survey among congress participants and pain physicians].Schmerz (Berlin, Germany) · 2021Article
- [Pain prevention in the primary care setting : Facts for resident physicians].Schmerz (Berlin, Germany) · 2021Review
- The Incidence of Mental Disorders Increases over Time in Patients with Cancer Pain: Data from a Retrospective Cohort Study.Pain research & management · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDue to advances in oncological therapy options and increasing survival rates, the number of cancer patients with persistant pain, who are in need of analgesic therapy has increased. It has been proven that biopsychosocial mechanisms exist in patients with persistant non-cancer pain leading to chronification. Furthermore, addiction has been identified as a complication of analgesic therapy.
objectiveCan the multidimensional model of chronic pain enhancement and chronification be used for patients with cancer pain, analogue to patients with non-cancer pain? Can addiction sydromes as a result of analgesic treatment be demonstrated? MATERIAL AND
methodsIn this non-systematic review, a literature search was carried out for somatic and psychosocial chronification mechanisms in patients with cancer pain. Indications for potential addiction syndromes in cancer patients are demonstrated based on selected publications. A Medline search provided a number of relevant publications that are listed (see Supplementary Material). RESULTS AND DISCUSSION: Somatic chronification mechanisms, such as pain intensity, repetitive algesic stimuli, topical and demographic factors, are found both in persistant non-cancer pain and cancer pain. Cancer-induced peripheral and central sensitization mechanisms that can be due to underlying genetic variations, are specific for cancer pain. With regard to psychosocial determinants for pain chronification, both cancer and non-cancer patients show similar patterns. Furthermore, data from the literature support the existence of addiction in cancer patients.
conclusionIn order to optimize treatment more attention should be paid to the risk of chronification and addiction in cases of chronic persistant cancer pain.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.