Evidence map›Paper›PMID 27832318›Full record

ArticleCancer immunology, immunotherapy : CII2017

Immunological effects of a novel RNA-based adjuvant in liver cancer patients.

Luisa Circelli, Annacarmen Petrizzo, Maria Tagliamonte, Regina Heidenreich, Maria Lina Tornesello, Franco M Buonaguro, Luigi Buonaguro

Open access · greenAbstract read
In one paragraph

Article in Cancer immunology, immunotherapy : CII, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Peptide-based vaccine for cancer therapies.Frontiers in immunology · 2023
    Review
  3. Article
  4. Review
  5. Article
  6. Systemic therapies for salivary gland adenoid cystic carcinoma.American journal of cancer research · 2021
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Review
  14. Use of adjuvants for immunotherapy.Human vaccines & immunotherapeutics · 2017
    Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Luisa CircelliExper. Immunotherapy Lab., Molecular Biology and Viral Oncogenesis Unit, Istituto Nazionale per lo Studio e la Cura dei Tumori, "Fondazione Pascale" - Istituto di Ricovero e Cura a Caratteres Scientifico (IRCCS), Naples, Italy.
Annacarmen PetrizzoExper. Immunotherapy Lab., Molecular Biology and Viral Oncogenesis Unit, Istituto Nazionale per lo Studio e la Cura dei Tumori, "Fondazione Pascale" - Istituto di Ricovero e Cura a Caratteres Scientifico (IRCCS), Naples, Italy.
Maria TagliamonteExper. Immunotherapy Lab., Molecular Biology and Viral Oncogenesis Unit, Istituto Nazionale per lo Studio e la Cura dei Tumori, "Fondazione Pascale" - Istituto di Ricovero e Cura a Caratteres Scientifico (IRCCS), Naples, Italy.
Regina HeidenreichCureVac AG, Tübingen, Germany.
Maria Lina TorneselloExper. Immunotherapy Lab., Molecular Biology and Viral Oncogenesis Unit, Istituto Nazionale per lo Studio e la Cura dei Tumori, "Fondazione Pascale" - Istituto di Ricovero e Cura a Caratteres Scientifico (IRCCS), Naples, Italy.
Franco M BuonaguroExper. Immunotherapy Lab., Molecular Biology and Viral Oncogenesis Unit, Istituto Nazionale per lo Studio e la Cura dei Tumori, "Fondazione Pascale" - Istituto di Ricovero e Cura a Caratteres Scientifico (IRCCS), Naples, Italy.
Luigi BuonaguroExper. Immunotherapy Lab., Molecular Biology and Viral Oncogenesis Unit, Istituto Nazionale per lo Studio e la Cura dei Tumori, "Fondazione Pascale" - Istituto di Ricovero e Cura a Caratteres Scientifico (IRCCS), Naples, Italy. l.buonaguro@istitutotumori.na.it.ORCID 0000-0002-6380-7114
Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale" · ITCureVac (Germany) · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Evaluation of biological effects of adjuvants on immune cells has been assessed in a limited number of studies. Moreover, no data are available on samples derived from cancer patients who may have a severe immune impairment. The effects of a novel RNA-based adjuvant (RNAdjuvant

Indexed as

Adjuvants, ImmunologicCancer VaccinesCarcinoma, HepatocellularFemaleHumansImmunotherapyLiver NeoplasmsMaleRNAAdjuvants, ImmunologicCancer VaccinesRNACancer vaccineHepatocellular carcinomaImmune responseRNAdjuvant

Identifiers

PMID27832318
PMCPMC11028778
OpenAlexW2552598756

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.