Evidence map›Paper›PMID 27832063›Full record

ArticlePLoS neglected tropical diseases2016

One Health Interactions of Chagas Disease Vectors, Canid Hosts, and Human Residents along the Texas-Mexico Border.

Melissa N Garcia, Sarah O'Day, Susan Fisher-Hoch, Rodion Gorchakov, Ramiro Patino, Teresa P Feria Arroyo, Susan T Laing, Job E Lopez, Alexandra Ingber, Kathryn M Jones and 1 more

Open access · goldAbstract read
In one paragraph

Article in PLoS neglected tropical diseases, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.

  1. Prevalence ofFrontiers in veterinary science · 2025
    Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Chagas Disease: A Silent Threat for Dogs and Humans.International journal of molecular sciences · 2024
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. PATHOLOGY AND DISCRETE TYPING UNIT ASSOCIATIONS OFJournal of wildlife diseases · 2020
    Article
  16. Review
  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Melissa N GarciaDepartment of Pediatrics, Section of Pediatric Tropical Medicine, National School of Tropical Medicine, Baylor College of Medicine and Texas Children's Hospital, Houston, Texas, United States of America.
Sarah O'DayThe University of Texas Health Science Center at Houston, School of Public Health, Houston, Texas, United States of America.
Susan Fisher-HochThe University of Texas Health Science Center, School of Public Health, Brownsville Regional Campus, Brownsville, Texas, United States of America.
Rodion GorchakovDepartment of Pediatrics, Section of Pediatric Tropical Medicine, National School of Tropical Medicine, Baylor College of Medicine and Texas Children's Hospital, Houston, Texas, United States of America.
Ramiro PatinoThe University of Texas Rio Grande Valley, Department of Biology, Edinburg, Texas, United States of America.
Teresa P Feria ArroyoThe University of Texas Rio Grande Valley, Department of Biology, Edinburg, Texas, United States of America.
Susan T LaingThe University of Texas Health Science Center at Houston, McGovern Medical School, Houston, Texas, United States of America.
Job E LopezDepartment of Pediatrics, Section of Pediatric Tropical Medicine, National School of Tropical Medicine, Baylor College of Medicine and Texas Children's Hospital, Houston, Texas, United States of America.
Alexandra IngberEmory University, Rollins School of Public Health, Atlanta, Georgia, United States of America.
Kathryn M JonesDepartment of Pediatrics, Section of Pediatric Tropical Medicine, National School of Tropical Medicine, Baylor College of Medicine and Texas Children's Hospital, Houston, Texas, United States of America.
Kristy O MurrayDepartment of Pediatrics, Section of Pediatric Tropical Medicine, National School of Tropical Medicine, Baylor College of Medicine and Texas Children's Hospital, Houston, Texas, United States of America.
Baylor College of Medicine · USThe University of Texas Health Science Center at Houston · USThe University of Texas Rio Grande Valley · USEmory University · USTexas Children's Hospital · US

Funding

TU SALUD SI CUENTA: A COMMUNITY BASED MEDIA INTERVENTION FOR MEXICAN AMERICANP20MD000170 · NIMHD · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI KELDER, STEVEN HAROLD · 2003 to 2012
$13.1M
UTPA RISE Undergraduate Training ProgramR25GM100866 · NIGMS · UNIVERSITY OF TEXAS RIO GRANDE VALLEY · PI DEARTH, ROBERT KEITH, PARSONS, JASON · 2012 to 2016
$1.8M
Prevalence of Chagas in Patients with Dilated CardiomyopathyR21AI114877 · NIAID · BAYLOR COLLEGE OF MEDICINE · PI MURRAY, KRISTY · 2015 to 2016
$438k
NCCDPHP CDC HHS R01 DP000210NIAID NIH HHS R21 AI114877NIGMS NIH HHS R25 GM100866NIMHD NIH HHS P20 MD000170
6 · The paper itself

Abstract

backgroundChagas disease (Trypanosoma cruzi infection) is the leading cause of non-ischemic dilated cardiomyopathy in Latin America. Texas, particularly the southern region, has compounding factors that could contribute to T. cruzi transmission; however, epidemiologic studies are lacking. The aim of this study was to ascertain the prevalence of T. cruzi in three different mammalian species (coyotes, stray domestic dogs, and humans) and vectors (Triatoma species) to understand the burden of Chagas disease among sylvatic, peridomestic, and domestic cycles. METHODOLOGY/PRINCIPAL

findingsTo determine prevalence of infection, we tested sera from coyotes, stray domestic dogs housed in public shelters, and residents participating in related research studies and found 8%, 3.8%, and 0.36% positive for T. cruzi, respectively. PCR was used to determine the prevalence of T. cruzi DNA in vectors collected in peridomestic locations in the region, with 56.5% testing positive for the parasite, further confirming risk of transmission in the region. CONCLUSIONS/SIGNIFICANCE: Our findings contribute to the growing body of evidence for autochthonous Chagas disease transmission in south Texas. Considering this region has a population of 1.3 million, and up to 30% of T. cruzi infected individuals developing severe cardiac disease, it is imperative that we identify high risk groups for surveillance and treatment purposes.

Indexed as

Global HealthHost-Parasite InteractionsInsect VectorsAnimalsAnimals, DomesticChagas DiseaseCost of IllnessCoyotesDogsHousingHumansMexicoPolymerase Chain ReactionPrevalenceTexasTriatoma

Identifiers

PMID27832063
PMCPMC5104435
OpenAlexW2550944720

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.