Evidence map›Paper›PMID 27831798›Full record

ArticleAnnals of the American Thoracic Society2016

An Official American Thoracic Society Workshop Report: Evaluation and Management of Asthma in the Elderly.

Gwen S Skloot, Paula J Busse, Sidney S Braman, Elizabeth J Kovacs, Anne E Dixon, Carlos A Vaz Fragoso, Nicola Scichilone, Y S Prakash, Christina M Pabelick, Sameer K Mathur and 6 more

Open access · greenAbstract read
In one paragraph

Article in Annals of the American Thoracic Society, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 1 pooled it
6.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 1 synthesis or guideline pooled it, 107 citations in OpenAlex.

  1. Pooled it
  2. Observational
  3. Article
  4. Review
  5. Review
  6. Development and validation of a long-term survival prediction model for older adults with asthma.Archives of public health = Archives belges de sante publique · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Menopause is not associated with asthma or severe asthma.The journal of allergy and clinical immunology. In practice · 2025
    Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Management Reality of Female Patients with COPD: A Multicenter Cross-Sectional CAP Study in Japan.International journal of chronic obstructive pulmonary disease · 2024
    Observational
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 1 institution in 1 country.

Gwen S SklootThis official Workshop Report of the American Thoracic Society (ATS) was approved by the ATS Board of Directors, August 2016.
Paula J BusseThis official Workshop Report of the American Thoracic Society (ATS) was approved by the ATS Board of Directors, August 2016.
Sidney S BramanThis official Workshop Report of the American Thoracic Society (ATS) was approved by the ATS Board of Directors, August 2016.
Elizabeth J KovacsThis official Workshop Report of the American Thoracic Society (ATS) was approved by the ATS Board of Directors, August 2016.
Anne E DixonThis official Workshop Report of the American Thoracic Society (ATS) was approved by the ATS Board of Directors, August 2016.
Carlos A Vaz FragosoThis official Workshop Report of the American Thoracic Society (ATS) was approved by the ATS Board of Directors, August 2016.
Nicola ScichiloneThis official Workshop Report of the American Thoracic Society (ATS) was approved by the ATS Board of Directors, August 2016.
Y S PrakashThis official Workshop Report of the American Thoracic Society (ATS) was approved by the ATS Board of Directors, August 2016.
Christina M PabelickThis official Workshop Report of the American Thoracic Society (ATS) was approved by the ATS Board of Directors, August 2016.
Sameer K MathurThis official Workshop Report of the American Thoracic Society (ATS) was approved by the ATS Board of Directors, August 2016.
Nicola A HananiaThis official Workshop Report of the American Thoracic Society (ATS) was approved by the ATS Board of Directors, August 2016.
Wendy C MooreThis official Workshop Report of the American Thoracic Society (ATS) was approved by the ATS Board of Directors, August 2016.
Peter G GibsonThis official Workshop Report of the American Thoracic Society (ATS) was approved by the ATS Board of Directors, August 2016.
Susan ZiemanThis official Workshop Report of the American Thoracic Society (ATS) was approved by the ATS Board of Directors, August 2016.
Betina B RaglessThis official Workshop Report of the American Thoracic Society (ATS) was approved by the ATS Board of Directors, August 2016.
ATS ad hoc Committee on Asthma in the Elderly
American Chemical Society · US

Funding

Aging, macrophage mediators, and burn trauma: SupplementR01AG018859 · NIA · UNIVERSITY OF COLORADO DENVER · PI KOVACS, ELIZABETH J. · 2001 to 2024
$7.6M
NIA NIH HHS R01 AG018859
6 · The paper itself

Abstract

Asthma in the elderly (>65 yr old) is common and associated with higher morbidity and mortality than asthma in younger patients. The poor outcomes in this group are due, in part, to underdiagnosis and undertreatment. There are a variety of factors related to aging itself that affect the presentation of asthma in the elderly and influence diagnosis and management. Structural changes in the aging lung superimposed on structural changes due to asthma itself can worsen the disease and physiologic function. Changes in the aging immune system influence the cellular composition and function in asthmatic airways. These processes and differences from younger individuals with asthma are not well understood. Phenotypes of asthma in the elderly have not been clearly delineated, but it is likely that age of onset and overlap with chronic obstructive pulmonary disease impact disease characteristics. Physiologic tests and biomarkers used to diagnose and follow asthma in the elderly are generally similar to testing in younger individuals; however, whether they should be modified in aging has not been established. Confounding influences, such as comorbidities (increasing the risk of polypharmacy), impaired cognition and motor skills, psychosocial effects of aging, and age-related adverse effects of medications, impact both diagnosis and treatment of asthma in the elderly. Future efforts to understand asthma in the elderly must include geriatric-specific methodology to diagnose, characterize, monitor, and treat their disease.

Indexed as

AgingBiomarkersAgedAsthmaComorbidityDiagnosis, DifferentialDisease ManagementHumansImmunosenescenceLungPhenotypePulmonary Disease, Chronic ObstructiveSocieties, MedicalUnited StatesBiomarkersagingimmunosenescencelung functionphenotypereactive airways disease

Identifiers

PMID27831798
PMCPMC5466180
OpenAlexW2560538384

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.