Evidence map›Paper›PMID 27830524›Full record

SynthesisInfection2017

Association of HIV infection with extrapulmonary tuberculosis: a systematic review.

Rupak Shivakoti, Davina Sharma, Gabeena Mamoon, Kiemanh Pham

Open access · greenAbstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Infection, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 4 pooled it
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 4 syntheses or guidelines pooled it, 72 citations in OpenAlex.

  1. Pooled it
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  4. Gastrointestinal tuberculosis: A systematic review of epidemiology, presentation, diagnosis and treatment.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Rupak Shivakoti *Johns Hopkins School of Medicine, Baltimore, MD, USA.
Davina Sharma *Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Gabeena MamoonJohns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Kiemanh Pham *Johns Hopkins School of Medicine, Baltimore, MD, USA.
Johns Hopkins University · US

Funding

Maternal inflammation, diet and gut microbiome in HIV: impact on infant outcomesK99HD089753 · NICHD · JOHNS HOPKINS UNIVERSITY · PI SHIVAKOTI, RUPAK · 2016 to 2017
$262k
NICHD NIH HHS K99 HD089753
6 · The paper itself

Abstract

purposeHIV/AIDS is a known risk factor for the development of pulmonary tuberculosis (PTB). However, the association is less clear between HIV and extrapulmonary tuberculosis (EPTB). We conducted a systematic review to determine the association between HIV and EPTB.

methodsWe searched the electronic databases Medline, Embase, and relevant conference literature using defined search terms for EPTB and HIV. Only publications in English and only studies reporting adjusted estimates were included, while our search criteria did not include restriction by age or geographic location of study participants. Qualitative and quantitative analyses (including I

resultsSixteen studies (15 cross-sectional and 1 case-control) conducted from 1984 to 2016 were included in the final analyses after screening 5163 articles and conference abstracts. Our qualitative analysis showed heterogeneity in study design and study population characteristics along with a medium/high risk of bias in the majority of studies. While most of the individual studies showed increased odds of EPTB compared with PTB among HIV-infected individuals, we did not provide an overall pooled estimate, as the I

conclusionsWhile an association between HIV and EPTB is observed in most individual studies, the high heterogeneity and risk of bias in these studies highlight the need for further well-designed prospective cohort studies to assess the true risk of EPTB in the HIV-infected patient population.

Indexed as

HIV InfectionsTuberculosisAdolescentAdultAgedChildChild, PreschoolFemaleHumansInfantInfant, NewbornMaleMiddle AgedRisk FactorsYoung AdultEPTBHIVPulmonary TBSystematic reviewTB

Identifiers

PMID27830524
PMCPMC5303538
OpenAlexW2550731886

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.