Evidence map›Paper›PMID 27830455›Full record

ArticleBiomedical microdevices2016

Optimization of an endovascular magnetic filter for maximized capture of magnetic nanoparticles.

Sravani Kondapavulur, Andre M Cote, Kiel D Neumann, Caroline D Jordan, David McCoy, Marc C Mabray, Derek Liu, Chia-Hung Sze, Ayushi Gautam, Henry F VanBrocklin and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedical microdevices, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. 3D Printed Biosponge Adsorbers for Capturing Toxic Chemotherapy DrugsACS biomaterials science & engineering · 2026
    Article
  3. Article
  4. Quantification ofJournal of magnetic resonance imaging : JMRI · 2018
    Article
  5. A two-scale approach for CFD modeling of endovascular Chemofilter device.Biomechanics and modeling in mechanobiology · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Sravani KondapavulurDepartment of Radiology and Biomedical Imaging, University of California, 505 Parnassus Avenue, L-351, San Francisco, CA, 94143-0628, USA.
Andre M CoteDepartment of Radiology and Biomedical Imaging, University of California, 505 Parnassus Avenue, L-351, San Francisco, CA, 94143-0628, USA.
Kiel D NeumannDepartment of Radiology and Biomedical Imaging, University of California, 505 Parnassus Avenue, L-351, San Francisco, CA, 94143-0628, USA.
Caroline D JordanDepartment of Radiology and Biomedical Imaging, University of California, 505 Parnassus Avenue, L-351, San Francisco, CA, 94143-0628, USA.
David McCoyDepartment of Radiology and Biomedical Imaging, University of California, 505 Parnassus Avenue, L-351, San Francisco, CA, 94143-0628, USA.
Marc C MabrayDepartment of Radiology and Biomedical Imaging, University of California, 505 Parnassus Avenue, L-351, San Francisco, CA, 94143-0628, USA.
Derek LiuDepartment of Bioengineering, University of California, Berkeley, CA, USA.
Chia-Hung SzeDepartment of Radiology and Biomedical Imaging, University of California, 505 Parnassus Avenue, L-351, San Francisco, CA, 94143-0628, USA.
Ayushi GautamDepartment of Radiology and Biomedical Imaging, University of California, 505 Parnassus Avenue, L-351, San Francisco, CA, 94143-0628, USA.
Henry F VanBrocklinDepartment of Radiology and Biomedical Imaging, University of California, 505 Parnassus Avenue, L-351, San Francisco, CA, 94143-0628, USA.
Mark WilsonDepartment of Radiology and Biomedical Imaging, University of California, 505 Parnassus Avenue, L-351, San Francisco, CA, 94143-0628, USA.
Steven W HettsDepartment of Radiology and Biomedical Imaging, University of California, 505 Parnassus Avenue, L-351, San Francisco, CA, 94143-0628, USA. steven.hetts@ucsf.edu.

Funding

Clinical and Translational Science InstituteUL1TR001872 · NCATS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI COLLARD, HAROLD R, JACOBY, VANESSA · 2016 to 2025
$112.1M
MEDICAL SCIENTIST TRAINING PROGRAMT32GM007618 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI ANDERSON, MARK S · 1985 to 2020
$29.6M
Endovascular Magnetic Catheter for Interventional MRIR01EB012031 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HETTS, STEVEN WILLIAM, MARTIN, ALASTAIR J · 2011 to 2021
$4.8M
Endovascular Chemofiltration: Optimizing Removal of Chemotherapeutics and Nanoparticles from the Blood to Reduce ToxicityR01CA194533 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HETTS, STEVEN WILLIAM · 2015 to 2019
$2.6M
Immersive Team-Based Design in Undergraduate Bioengineering EducationR25EB013068 · NIBIB · UNIVERSITY OF CALIFORNIA BERKELEY · PI HERR, AMY ELIZABETH · 2011 to 2020
$379k
NCATS NIH HHS UL1 TR001872NCI NIH HHS R01 CA194533NIBIB NIH HHS R01 EB012031NIBIB NIH HHS R25 EB013068NIGMS NIH HHS T32 GM007618
6 · The paper itself

Abstract

To computationally optimize the design of an endovascular magnetic filtration device that binds iron oxide nanoparticles and to validate simulations with experimental results of prototype devices in physiologic flow testing. Three-dimensional computational models of different endovascular magnetic filter devices assessed magnetic particle capture. We simulated a series of cylindrical neodymium N52 magnets and capture of 1500 iron oxide nanoparticles infused in a simulated 14 mm-diameter vessel. Device parameters varied included: magnetization orientation (across the diameter, "D", along the length, "L", of the filter), magnet outer diameter (3, 4, 5 mm), magnet length (5, 10 mm), and spacing between magnets (1, 3 mm). Top designs were tested in vitro using

Indexed as

Magnetic FieldsBlood VesselsFerric CompoundsFiltrationNanoparticlesFerric Compoundsferric oxideChemofiltrationEndovascular deviceIntra-arterial chemotherapy (IAC)Magnetic nanoparticles

Identifiers

PMID27830455
PMCPMC5468174

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.