ArticleEuropean journal of applied physiology2017
Diurnal physiological and immunological responses to a 10-km run in highly trained athletes in an environmentally controlled condition of 6 °C.
Article in European journal of applied physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Exercise versus no exercise for the occurrence, severity, and duration of acute respiratory infections.The Cochrane database of systematic reviews · 2020Pooled it
- Continuous exercise induces airway epithelium damage while a matched-intensity and volume intermittent exercise does not.Respiratory research · 2019Trial
- Effects of inspiratory muscle training combined with circadian rhythm-based running programs in male children football players.BMC sports science, medicine & rehabilitation · 2026Article
- Maximizing performance in child footballers: chronotype and time of day study.Frontiers in physiology · 2025Article
- Club cell protein (CC16) in serum as an effect marker for small airway epithelial damage caused by diesel exhaust and blasting fumes in potash mining.International archives of occupational and environmental health · 2024Article
- Practical Recommendations Relevant to the Use of Resistance Training for COVID-19 Survivors.Frontiers in physiology · 2021Article
- Circadian rhythms and exercise - re-setting the clock in metabolic disease.Nature reviews. Endocrinology · 2019Review
- Article
- Pulmonary edema during the Boston Marathon.Respiratory medicine case reports · 2019Article
- Comprehensive proteome analysis of nasal lavage samples after controlled exposure to welding nanoparticles shows an induced acute phase and a nuclear receptor, LXR/RXR, activation that influence the status of the extracellular matrix.Clinical proteomics · 2018Article
- Diurnal Variation in Physiological and Immune Responses to Endurance Sport in Highly Trained Runners in a Hot and Humid Environment.Oxidative medicine and cellular longevity · 2018Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe Clara cell protein CC16, secreted from Clara cells in the lung, is discussed as a potential biomarker for toxic effects on the airways. An increased concentration of CC16 in serum may be caused by increased permeability of the lungs. To investigate the changes in P-CC16 in response to an intense exercise bout performed at different times of day (9 am and 4 pm) of highly trained individuals.
methodUsing a crossover randomized design, 8 runners (mean VO
resultDiurnal differences (P < 0.05) were found for blood neutrophil and lymphocyte counts; with higher values at 4 pm. P-CC16 was higher at the pre- and post-trial time point at 9 am compared to 4 pm. Lung function was not different between or within trials.
conclusionMorning trial in cold condition caused more physiological strain compared to the same trial in the evening. However, this extra stress caused by zeitgebers could be a useful strategy for athletes, coaches, and general population to improve their running performance and protect their health in cold conditions in the long-term plan.
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