ArticleNeuroImage. Clinical2016
Early grey matter changes in structural covariance networks in Huntington's disease.
Article in NeuroImage. Clinical, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.
- Localised grey matter atrophy in multiple sclerosis is network-based: a coordinate-based meta-analysis.Clinical radiology · 2019Pooled it
- Network-level structural alterations distinguish persistent from remitted post-traumatic stress disorder: a morphometric covariance approach.European journal of psychotraumatology · 2026Article
- Neural Mechanisms of Object Location Memory in Huntington's Disease.Movement disorders : official journal of the Movement Disorder Society · 2025Article
- Advances in Huntington's Disease Biomarkers: A 10-Year Bibliometric Analysis and a Comprehensive Review.Biology · 2025Review
- Associations of conservatism and jumping to conclusions biases with aberrant salience and default mode network.Psychiatry and clinical neurosciences · 2024Article
- Alterations in Brain Morphometric Networks and Their Relationship with Memory Dysfunction in Patients with Type 2 Diabetes Mellitus.Experimental neurobiology · 2024Article
- Pain in Huntington's disease and its potential mechanisms.Frontiers in aging neuroscience · 2023Review
- In-scanner head motion and structural covariance networks.Human brain mapping · 2022Article
- Mutation-related magnetization-transfer, not axon density, drives white matter differences in premanifest Huntington disease: Evidence from in vivo ultra-strong gradient MRI.Human brain mapping · 2022Article
- A Glimpse of Molecular Biomarkers in Huntington's Disease.International journal of molecular sciences · 2022Review
- Asymptomatic carotid stenosis is associated with both edge and network reconfigurations identified by single-subject cortical thickness networks.Frontiers in aging neuroscience · 2022Article
- Cingulate networks associated with gray matter loss in Parkinson's disease show high expression of cholinergic genes in the healthy brain.The European journal of neuroscience · 2021Article
- Dynamics of Cortical Degeneration Over a Decade in Huntington's Disease.Biological psychiatry · 2021Article
- INTEGRATIVE NETWORK LEARNING FOR MULTI-MODALITY BIOMARKER DATA.The annals of applied statistics · 2021Article
- Altered iron and myelin in premanifest Huntington's Disease more than 20 years before clinical onset: Evidence from the cross-sectional HD Young Adult Study.EBioMedicine · 2021Article
- Volumetric MRI-Based Biomarkers in Huntington's Disease: An Evidentiary Review.Frontiers in neurology · 2021Review
- Covarying patterns of white matter lesions and cortical atrophy predict progression in early MS.Neurology(R) neuroimmunology & neuroinflammation · 2020Article
- The Role of Hypothalamic Pathology for Non-Motor Features of Huntington's Disease.Journal of Huntington's disease · 2019Review
- Progressive microstructural changes of the occipital cortex in Huntington's disease.Brain imaging and behavior · 2018Article
- BrainMap VBM: An environment for structural meta-analysis.Human brain mapping · 2018Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundProgressive subcortical changes are known to occur in Huntington's disease (HD), a hereditary neurodegenerative disorder. Less is known about the occurrence and cohesion of whole brain grey matter changes in HD.
objectivesWe aimed to detect network integrity changes in grey matter structural covariance networks and examined relationships with clinical assessments.
methodsStructural magnetic resonance imaging data of premanifest HD (
resultsPremanifest HD and HD patients showed decreased network integrity in two networks compared to controls. One network included the caudate nucleus, precuneous and anterior cingulate cortex (in HD
conclusionOur results suggest that structural covariance might be a sensitive approach to reveal early grey matter changes, especially for premanifest HD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.