Evidence map›Paper›PMID 27830070›Full record

ArticleClinical case reports2016

Recurrent transient global amnesia as presenting symptoms of CADASIL.

Luca Pradotto, Laura Orsi, Monica Mencarelli, Marcella Caglio, Danilo Lauro, Alessandra Milesi, Anna Di Blasio, Alessandro Mauro

Open access · goldAbstract readCase Reports
In one paragraph

Article in Clinical case reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 12 citations in OpenAlex.

  1. First report of a homozygous mutation on exon 24 of the NOTCH3 gene in a paucisymptomatic CADASIL elderly patient.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022
    Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Luca PradottoDivision of Neurology and Neurorehabilitation San Giuseppe Hospital IRCCS Istituto Auxologico Italiano Piancavallo VB Italy.
Laura OrsiNeurologic Division 1 Department of Neuroscience and Mental Health AOU Città della Salute e della Scienza di Torino Turin Italy.
Monica MencarelliLaboratory of Molecular Biology IRCCS Istituto Auxologico Italiano Milan Italy.
Marcella CaglioDepartment of Neuroscience University of Turin Turin Italy.
Danilo LauroSurgical Dermatology Department of Oncology AOU Città della Salute e della Scienza di Torino Turin Italy.
Alessandra MilesiDivision of Neurology and Neurorehabilitation San Giuseppe Hospital IRCCS Istituto Auxologico Italiano Piancavallo VB Italy.
Anna Di BlasioLaboratory of Molecular Biology IRCCS Istituto Auxologico Italiano Milan Italy.
Alessandro MauroDivision of Neurology and Neurorehabilitation San Giuseppe HospitalI RCCS Istituto Auxologico Italiano Piancavallo VB Italy; Department of Neuroscience University of Turin Turin Italy.
Azienda Ospedaliera Citta' della Salute e della Scienza di Torino · ITIRCCS Istituto Auxologico Italiano · ITIstituti di Ricovero e Cura a Carattere Scientifico · ITOspedale San Giuseppe · ITUniversity of Turin · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite transient global amnesia is considered unusual in Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) and causal relation is still unclear, this report suggests to consider CADASIL in those patients with recurrent transient global amnesia, especially when MRI shows multifocal hyperintensities affecting the cerebral white matter or when it is followed by cognitive decline.

Indexed as

CADASILcognitive impairmentdementialeukoaraiosismicrobleedsNOTCH3 gene mutationtransient global amnesia

Identifiers

PMID27830070
PMCPMC5093160
OpenAlexW2526621909

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.