ArticleWorld journal of gastrointestinal surgery2016
Peptide-based enteral formula improves tolerance and clinical outcomes in abdominal surgery patients relative to a whole protein enteral formula.
Article in World journal of gastrointestinal surgery, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 32 citations in OpenAlex.
- Effect of high-protein peptide-based formula compared with isocaloric isonitrogenous polymeric formula in critically ill surgical patient.World journal of gastrointestinal surgery · 2024Trial
- Comparative efficacy of peptide-based versus standard polymeric enteral nutrition in ICU patients at high nutritional risk: a multicenter randomized controlled trial.Scientific reports · 2024Trial
- Implementation of an Enteral Nutrition Protocol in the Cardiac Care Unit - A Retrospective Study of Critically Ill Cardiovascular Patients.Circulation reports · 2026Article
- Article
- Semi-elemental versus polymeric formula for enteral nutrition in critically ill patients: a secondary analysis of a multicenter cluster-randomized controlled trial.Frontiers in nutrition · 2025Article
- Consensus-based recommendations for optimizing perioperative nutritional support and muscle health in major surgery in India.Frontiers in nutrition · 2025Article
- Enteral Nutrition Therapy: Historical Perspective, Utilization, and Complications.Current gastroenterology reports · 2024Review
- Protein Supplements with Short Peptides Are Better than Complex Protein-Based Supplements on Improving Early Fat-Free Mass Loss Following Bariatric Surgery: A Retrospective Cohort Study.Obesity surgery · 2024Article
- Protein Supplementation with Short Peptides Prevents Early Muscle Mass Loss after Roux-en-Y-Gastric Bypass.Nutrients · 2022Article
- Nutritional Support in Malnourished Children With Compromised Gastrointestinal Function: Utility of Peptide-Based Enteral Therapy.Frontiers in pediatrics · 2021Review
- Article
- Peptide-based formula versus standard-based polymeric formula for critically ill children: is it superior for patients' tolerance?Archives of medical science : AMS · 2020Article
- Early introduction of a semi-elemental formula may be cost saving compared to a polymeric formula among critically ill patients requiring enteral nutrition: a cohort cost-consequence model.ClinicoEconomics and outcomes research : CEOR · 2018Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo compare a dipeptide- and tripeptide-based enteral formula with a standard enteral formula for tolerance and nutritional outcomes in abdominal surgery patients.
methodsA retrospective study was performed to assess the differences between a whole-protein formula (WPF) and a dipeptide- and tripeptide-based formula (PEF) in clinical outcomes. Seventy-two adult intensive care unit (ICU) patients with serum albumin concentrations less than 3.0 g/dL were enrolled in this study. Patients were divided into two groups (WPF group = 40 patients, PEF group = 32 patients). The study patients were fed for at least 7 d, with ≥ 1000 mL of enteral formula infused on at least 3 of the days.
resultsThe mean serum albumin level on postoperative day (POD) 10, prealbumin levels on POD-5 and POD-10, and total lymphocyte count on POD-5 were significantly higher in the PEF group compared to those in the WPF group (
conclusionDipeptide- and tripeptide-based enteral formulas are more efficacious and better tolerated than whole-protein formulas.
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Registered trials
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