ArticleWorld journal of gastrointestinal surgery2016
Incidental non-benign gallbladder histopathology after cholecystectomy in an United Kingdom population: Need for routine histological analysis?
Article in World journal of gastrointestinal surgery, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
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Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 32 citations in OpenAlex.
- Selective or Routine Histology of Cholecystectomy Specimens for Diagnosing Incidental Carcinoma of Gallbladder and Correlation with Careful Intraoperative Macroscopic Examination? A Systematic Review.Asian Pacific journal of cancer prevention : APJCP · 2021Pooled it
- Safe, selective histopathological examination of gallbladder specimens: a systematic review.The British journal of surgery · 2020Pooled it
- Gallbladder osseous metaplasia mimicking a focal lesion on ultrasound: a case report of a rare benign condition.Journal of surgical case reports · 2026Article
- Differential diagnosis of gallbladder cholesterol polyps and adenomas using contrast-enhanced ultrasound-morphology and perfusion features.Abdominal radiology (New York) · 2026Article
- A Narrative Review of Selective Versus Routine Histopathological Examination of Gallbladders in Low-Risk Patients.Cureus · 2025Review
- Gallbladder Polyp and Cancer Evaluation After Cholecystectomy: A Retrospective Observational Study.Cureus · 2022Article
- A Nomogram-based Model to Predict Neoplastic Risk for Patients with Gallbladder Polyps.Journal of clinical and translational hepatology · 2022Article
- Safety and economic analysis of selective histopathology following cholecystectomy: multicentre, prospective, cross-sectional FANCY study.The British journal of surgery · 2022Article
- BRAZILIAN CONSENSUS ON INCIDENTAL GALLBLADDER CARCINOMA.Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2020Article
- Incidental Carcinoma after Cholecystectomy for Benign Disease of the Gallbladder: A Meta-Analysis.Journal of clinical medicine · 2020Article
- A Comparison Between the Prognosis of Simultaneous and Salvage Radical Resection in Incidental Gallbladder Cancer.Cancer management and research · 2020Article
- Bile spillage and incidental gall bladder adenocarcinoma.Hepatobiliary surgery and nutrition · 2019Article
- Article
- Distribution of dysplasia and cancer in the gallbladder: an analysis from a high cancer-risk population.Human pathology · 2018Article
- Routine Pathology and Postoperative Follow-Up are Not Cost-Effective in Cholecystectomy for Benign Gallbladder Disease.World journal of surgery · 2018Article
Corrections and comments
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Authors and funding
13 authors at 2 institutions in 2 countries.
Funding
Abstract
aimTo analyse the range of histopathology detected in the largest published United Kingdom series of cholecystectomy specimens and to evaluate the rational for selective histopathological analysis.
methodsIncidental gallbladder malignancy is rare in the United Kingdom with recent literature supporting selective histological assessment of gallbladders after routine cholecystectomy. All cholecystectomy gallbladder specimens examined by the histopathology department at our hospital during a five year period between March 2008 and March 2013 were retrospectively analysed. Further data was collected on all specimens demonstrating carcinoma, dysplasia and polypoid growths.
resultsThe study included 4027 patients. The majority (97%) of specimens exhibited gallstone or cholecystitis related disease. Polyps were demonstrated in 44 (1.09%), the majority of which were cholesterol based (41/44). Dysplasia, ranging from low to multifocal high-grade was demonstrated in 55 (1.37%). Incidental primary gallbladder adenocarcinoma was detected in 6 specimens (0.15%, 5 female and 1 male), and a single gallbladder revealed carcinoma
conclusionRoutine histological evaluation of all elective and emergency cholecystectomies is justified in a United Kingdom population as selective analysis has potential to miss potentially curable life threatening pathology.
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