Evidence map›Paper›PMID 27830006›Full record

ArticleAmerican journal of translational research2016

Mutation near the binding interfaces at α-hemoglobin stabilizing protein is highly pathogenic.

Jesu Francis Borgio, Mohammed S Al-Madan, Sayed AbdulAzeez

Open access · greenAbstract read
In one paragraph

Article in American journal of translational research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Molecular simulation studies on B-cell lymphoma/leukaemia 11A (BCL11A).American journal of translational research · 2019
    Article
  9. Article
  10. Review
  11. Archives of medical science : AMS · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Jesu Francis BorgioDepartment of Genetic Research, Institute for Research and Medical Consultation (IRMC), University of Dammam Dammam, Saudi Arabia.
Mohammed S Al-MadanDepartment of Pediatrics, King Fahd Hospital of the University Al-Khobar, Saudi Arabia.
Sayed AbdulAzeezDepartment of Genetic Research, Institute for Research and Medical Consultation (IRMC), University of Dammam Dammam, Saudi Arabia.
Imam Abdulrahman Bin Faisal University · SAKing Fahd Hospital of the University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aggregation of free alpha-hemoglobin proteins forms harmful reactive oxygen radicals during the development of normal erythroid cell, which can be prevented by a chaperone, alpha hemoglobin stabilizing protein (AHSP). Mutations at the

Indexed as

bioinformaticsglobin genesinteraction sitesinterface residuesmolecular modelingmutationnsSNPsprotein-protein interactionα-Hemoglobin stabilizing protein (AHSP)

Identifiers

PMID27830006
PMCPMC5095315
OpenAlexW2563917061

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.