Evidence map›Paper›PMID 27829988›Full record

ReviewAmerican journal of translational research2016

Targeting gut microbiota: a potential promising therapy for diabetic kidney disease.

Zhonge Chen, Shuishan Zhu, Gaosi Xu

Erratum issuedAbstract readReview
In one paragraph

Review in American journal of translational research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Human Gut Microbiota in Health and Selected Cancers.International journal of molecular sciences · 2021
    Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. How Ocular Surface Microbiota Debuts in Type 2 Diabetes Mellitus.Frontiers in cellular and infection microbiology · 2019
    Article
  11. Review
  12. Review
  13. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Zhonge ChenMedical Center of The Graduate School, Nanchang University Nanchang, China.
Shuishan ZhuDepartment of Gastroenterology, Second Affiliated Hospital, Nanchang University Nanchang, China.
Gaosi XuDepartment of Nephrology, Second Affiliated Hospital, Nanchang University Nanchang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Conventional studies reveal a contributory role of gut microbiota in the process of diabetes mellitus (DM) and end-stage renal disease (ESRD). However, the mechanism through which gut microbiota influence diabetic kidney disease (DKD) is ignored. In the present article, we reviewed the changes in gut microbiota of patients with DM, DKD as well as ESRD, and how this may contribute to the progression of DKD. Although further studies are needed to either selectively change the composition of the gut microbiota or to pharmacologically control the metabolites of microbiota, the gut microbiota represents a new potential therapeutic target for DKD.

Indexed as

diabetes mellitusdiabetic kidney diseaseend-stage renal diseaseGut microbiota

Identifiers

PMID27829988
PMCPMC5095297

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.