Evidence map›Paper›PMID 27829428›Full record

Trial reportBMC complementary and alternative medicine2016

Aromatherapy for the treatment of PONV in children: a pilot RCT.

Mathew B Kiberd, Suzanne K Clarke, Jill Chorney, Brandon d'Eon, Stuart Wright

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC complementary and alternative medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02663154 (Aromatherapy for Postoperative Nausea and Vomiting in Children), which is not on this map. Cited by 9 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 3 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02663154 phase2completednot on this map

Aromatherapy for Postoperative Nausea and Vomiting in Children: A Single Blind Randomized Clinical Trial

TypeinterventionalSponsorStuart WrightRan2014 to 2015Enrolled39ConditionsPostoperative Nausea and VomitingArmsAromatherapy inhaler, Saline inhaler
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 3 syntheses or guidelines pooled it, 32 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Aromatherapy for treatment of postoperative nausea and vomiting.The Cochrane database of systematic reviews · 2018
    Pooled it
  4. Article
  5. Article
  6. Review
  7. Aromatherapy for test anxiety in chiropractic students.The Journal of chiropractic education · 2021
    Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Mathew B KiberdDepartment of Anesthesia, Pain Management and Perioperative Medicine, Dalhousie University, 1276 South Park Street, 231-C 10 West Victoria Building, Halifax, NS, B3H 2Y9, Canada. Mathew.kiberd@dal.ca.
Suzanne K ClarkeDepartment of Anesthesia, Pain Management and Perioperative Medicine, Dalhousie University, 1276 South Park Street, 231-C 10 West Victoria Building, Halifax, NS, B3H 2Y9, Canada.
Jill ChorneyDepartment of Anesthesia, Pain Management and Perioperative Medicine, Dalhousie University, 1276 South Park Street, 231-C 10 West Victoria Building, Halifax, NS, B3H 2Y9, Canada.
Brandon d'EonDepartment of Anesthesia, Pain Management and Perioperative Medicine, Dalhousie University, 1276 South Park Street, 231-C 10 West Victoria Building, Halifax, NS, B3H 2Y9, Canada.
Stuart WrightDepartment of Anesthesia, Pain Management and Perioperative Medicine, Dalhousie University, 1276 South Park Street, 231-C 10 West Victoria Building, Halifax, NS, B3H 2Y9, Canada.
Dalhousie University · CAIzaak Walton Killam Health Centre · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPostoperative nausea and vomiting (PONV) is one of the most common postoperative complications of general anesthesia in pediatrics. Aromatherapy has been shown to be effective in treating PONV in adults. Given the encouraging results of the adult studies, we planned to determine feasibility of doing a large-scale study in the pediatric population.

methodsOur group conducted a pilot randomized controlled trial examining the effect of aromatherapy on post-operative nausea and vomiting in patients 4-16 undergoing ambulatory surgery at a single center. Nausea was defined as a score of 4/10 on the Baxter Retching Faces Scale (BARF scale). A clinically significant reduction was defined as a two-point reduction in Nausea. Post operatively children were administered the BARF scale in 15 min internals until discharge home or until nausea score of 4/10 or greater. Children with nausea were randomized to saline placebo group or aromatherapy QueaseEase™ (Soothing Scents, Inc, Enterprise, AL: blend of ginger, lavender, mint and spearmint). Nausea scores were recorded post intervention.

resultsA total of 162 subjects were screened for inclusion in the study. Randomization occurred in 41 subjects of which 39 were included in the final analysis. For the primary outcome, 14/18 (78 %) of controls reached primary outcome compared to 19/21 (90 %) in the aromatherapy group (p = 0.39, Eta 0.175). Other outcomes included use of antiemetic in PACU (control 44 %, aromatherapy 52 % P = 0.75, Eta 0.08), emesis (Control 11 %, 9 % aromatherapy, P = 0.87, Eta = 0.03). There was a statistically significant difference in whether subjects continued to use the intervention (control 28 %, aromatherapy 66 %, p-value 0.048, Eta 0.33).

conclusionAromatherapy had a small non-significant effect size in treating postoperative nausea and vomiting compared with control. A large-scale randomized control trial would not be feasible at our institution and would be of doubtful utility.

trial registrationClinicalTrials.gov NCT02663154 .

Indexed as

AromatherapyAdministration, InhalationAdolescentAmbulatory Surgical ProceduresChildChild, PreschoolFemaleHumansMaleOils, VolatilePilot ProjectsPlant OilsPostoperative Nausea and VomitingOils, VolatilePlant OilsAmbulatory surgical proceduresAntiemeticsAromatherapyComplementary therapiesMeSH postoperative nausea and vomitingNauseaPediatrics

Identifiers

PMID27829428
PMCPMC5103370
OpenAlexW2555932543

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.