Evidence map›Paper›PMID 27829164›Full record

ArticleToxicology in vitro : an international journal published in association with BIBRA2017

Molecular effects of 1-naphthyl-methylcarbamate and solar radiation exposures on human melanocytes.

Bianca Ferrucio, Manoela Tiago, Richard D Fannin, Liwen Liu, Kevin Gerrish, Silvya Stuchi Maria-Engler, Richard S Paules, Silvia Berlanga de Moraes Barros

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Toxicology in vitro : an international journal published in association with BIBRA, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Melanoma Risk and Melanocyte Biology.Acta dermato-venereologica · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Bianca FerrucioDepartment of Clinical Chemistry and Toxicology, School of Pharmaceutical Sciences, University of São Paulo, São Paulo, SP, Brazil, 05508-000. Electronic address: biferrucio@usp.br.
Manoela TiagoDepartment of Clinical Chemistry and Toxicology, School of Pharmaceutical Sciences, University of São Paulo, São Paulo, SP, Brazil, 05508-000. Electronic address: manoela.santos@usp.br.
Richard D FanninNIEHS Molecular Genomics Core Laboratory, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA, 27709. Electronic address: fannin@niehs.nih.gov.
Liwen LiuNIEHS Molecular Genomics Core Laboratory, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA, 27709. Electronic address: liuliw@niehs.nih.gov.
Kevin GerrishNIEHS Molecular Genomics Core Laboratory, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA, 27709. Electronic address: gerrish@niehs.nih.gov.
Silvya Stuchi Maria-EnglerDepartment of Clinical Chemistry and Toxicology, School of Pharmaceutical Sciences, University of São Paulo, São Paulo, SP, Brazil, 05508-000. Electronic address: silvya@usp.br.
Richard S PaulesNIEHS Molecular Genomics Core Laboratory, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA, 27709. Electronic address: paules@niehs.nih.gov.
Silvia Berlanga de Moraes BarrosDepartment of Clinical Chemistry and Toxicology, School of Pharmaceutical Sciences, University of São Paulo, São Paulo, SP, Brazil, 05508-000. Electronic address: smbarros@usp.br.
National Institute of Environmental Health Sciences · USUniversidade de São Paulo · BR

Funding

Gene Expression and MicroarraysZICES102445 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI GERRISH, KEVIN · 2009 to 2025
$31.6M
Biomolecular Screening and Alternative Approaches for the National Toxicology ProgramZIAES103318 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI CASEY, WARREN · 2016 to 2021
$25.0M
Molecular Analysis Of Cell Cycle Control in CarcinogenesZ01ES021157 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI PAULES, RICHARD S · 1991 to 2008
$1.7M
Microarray Tech / Understanding Environmental AgentsZ01ES023026 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI PAULES, RICHARD S · 1999 to 2008
$688k
Intramural NIH HHS Z01 ES021157Intramural NIH HHS Z01 ES023026
6 · The paper itself

Abstract

Carbaryl (1-naphthyl-methylcarbamate), a broad-spectrum insecticide, has recently been associated with the development of cutaneous melanoma in an epidemiological cohort study with U.S. farm workers also exposed to ultraviolet radiation, the main etiologic factor for skin carcinogenesis. We hypothesized that carbaryl exposure may increase deleterious effects of UV solar radiation on skin melanocytes. This study aimed to characterize human melanocytes after individual or combined exposure to carbaryl (100μM) and solar radiation (375mJ/cm

Indexed as

ApoptosisCarbarylCell CycleCell DivisionCells, CulturedCell SurvivalChildChild, PreschoolDNA DamageEndoplasmic Reticulum StressHumansMaleMelanocytesOxidative StressSunlightUltraviolet RaysCarbaryl1-naphthyl-methylcarbamateCarbarylMelanocytesMelanomagenesisMicroarraySolar radiation

Identifiers

PMID27829164
PMCPMC6158021
OpenAlexW2548505820

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.