Evidence map›Paper›PMID 27829034›Full record

ArticlePloS one2016

Auditory-Motor Mapping Training: Comparing the Effects of a Novel Speech Treatment to a Control Treatment for Minimally Verbal Children with Autism.

Karen Chenausky, Andrea Norton, Helen Tager-Flusberg, Gottfried Schlaug

Registry-linked trialOpen access · goldAbstract readComparative Study
In one paragraph

Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03015272 (Testing a Novel Speech Intervention in Minimally Verbal Children With Autism Spectrum Disorder), which is not on this map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03015272 phase2 / phase3completednot on this map

Testing a Novel Speech Intervention in Minimally Verbal Children With Autism Spectrum Disorder (ASD)

TypeinterventionalSponsorBeth Israel Deaconess Medical CenterRan2014 to 2019Enrolled14ConditionsAutismArmsAuditory-Motor Mapping Training, Speech-Repetition Therapy
3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.

  1. Pooled it
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  6. Review
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  11. Vowel distinctiveness as a concurrent predictor of expressive language function in autistic children.Autism research : official journal of the International Society for Autism Research · 2024
    Article
  12. Oromotor skills in autism spectrum disorder: A scoping review.Autism research : official journal of the International Society for Autism Research · 2023
    Article
  13. Article
  14. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Karen ChenauskyMusic and Neuroimaging Laboratory, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, United States of America.
Andrea NortonMusic and Neuroimaging Laboratory, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, United States of America.
Helen Tager-FlusbergCenter for Autism Research Excellence, Department of Psychological and Brain Sciences, Boston University, Boston, United States of America.
Gottfried SchlaugMusic and Neuroimaging Laboratory, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, United States of America.
Harvard University · USCenter for Autism and Related Disorders · US

Funding

Testing the efficacy of a novel intervention for minimally verbal children with P50DC013027 · NIDCD · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI SHINN-CUNNINGHAM, BARBARA · 2012 to 2016
$9.4M
Neurobehavioral Research on Infants at Risk for SLI and AutismR01DC010290 · NIDCD · BOSTON UNIVERSITY MEDICAL CAMPUS · PI NELSON, CHARLES ALEXANDER, TAGER-FLUSBERG, HELEN · 2009 to 2020
$7.5M
NIDCD NIH HHS P50 DC013027NIDCD NIH HHS R01 DC010290
6 · The paper itself

Abstract

This study compared Auditory-Motor Mapping Training (AMMT), an intonation-based treatment for facilitating spoken language in minimally verbal children with autism spectrum disorder (ASD), to a matched control treatment, Speech Repetition Therapy (SRT). 23 minimally verbal children with ASD (20 male, mean age 6;5) received at least 25 sessions of AMMT. Seven (all male) were matched on age and verbal ability to seven participants (five male) who received SRT. Outcome measures were Percent Syllables Approximated, Percent Consonants Correct (of 86), and Percent Vowels Correct (of 61) produced on two sets of 15 bisyllabic stimuli. All subjects were assessed on these measures several times at baseline and after 10, 15, 20, and 25 sessions. The post-25 session assessment timepoint, common to all participants, was compared to Best Baseline performance. Overall, after 25 sessions, AMMT participants increased by 19.4% Syllables Approximated, 13.8% Consonants Correct, and19.1% Vowels Correct, compared to Best Baseline. In the matched AMMT-SRT group, after 25 sessions, AMMT participants produced 29.0% more Syllables Approximated (SRT 3.6%);17.9% more Consonants Correct (SRT 0.5); and 17.6% more Vowels Correct (SRT 0.8%). Chi-square tests showed that significantly more AMMT than SRT participants in both the overall and matched groups improved significantly in number of Syllables Approximated per stimulus and number of Consonants Correct per stimulus. Pre-treatment ability to imitate phonemes, but not chronological age or baseline performance on outcome measures, was significantly correlated with amount of improvement after 25 sessions. Intonation-based therapy may offer a promising new interventional approach for teaching spoken language to minimally verbal children with ASD.

Indexed as

Analysis of VarianceAuditory CortexAutistic DisorderChildChild, PreschoolFemaleHumansLanguage Development DisordersLanguage TherapyMaleMotor CortexOutcome Assessment, Health CareSpeechSpeech DisordersSpeech PerceptionSpeech Therapy

Identifiers

PMID27829034
PMCPMC5102445
OpenAlexW2556385324

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.