Evidence map›Paper›PMID 27828872›Full record

ArticleJournal of acquired immune deficiency syndromes (1999)2017

Sexual Behavior and Vaginal Practices During Pregnancy and Postpartum: Implications for HIV Prevention Strategies.

John Kinuthia, Barbra A Richardson, Alison L Drake, Daniel Matemo, Jennifer A Unger, Raymond S McClelland, Grace John-Stewart

Open access · greenAbstract read
In one paragraph

Article in Journal of acquired immune deficiency syndromes (1999), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

John KinuthiaDepartments of *Research and Programs; †Reproductive Health, Kenyatta National Hospital, Nairobi, Kenya; and Departments of ‡Biostatistics; §Global Health, University of Washington, Seattle, WA.
Barbra A Richardson
Alison L Drake
Daniel Matemo
Jennifer A Unger
Raymond S McClelland
Grace John-Stewart
University of Washington · USCancer Research And Biostatistics · USKenyatta National Hospital · KE

Funding

University of Washington/Fred Hutch Center for AIDS ResearchP30AI027757 · NIAID · UNIVERSITY OF WASHINGTON · PI Kenneth Sherr · 1988 to 2026
$104.9M
Vaginal Health and the Risk of HIV-1 Acquistion in Kenyan WomenP01HD064915 · NICHD · FRED HUTCHINSON CANCER RESEARCH CENTER · PI JOHN-STEWART, GRACE C. · 2009 to 2013
$8.9M
Pediatric HIV-1 in Africa: Pathogenesis and ManagementK24HD054314 · NICHD · UNIVERSITY OF WASHINGTON · PI JOHN-STEWART, GRACE C. · 2006 to 2016
$1.2M
Optimizing repeat HIV testing during pregnancy and postpartum for PMTCTK01AI116298 · NIAID · UNIVERSITY OF WASHINGTON · PI DRAKE, ALISON L · 2015 to 2019
$632k
NIAID NIH HHS K01 AI116298NIAID NIH HHS P30 AI027757NICHD NIH HHS K24 HD054314NICHD NIH HHS P01 HD064915
6 · The paper itself

Abstract

backgroundUnderstanding sexual behaviors and vaginal practices of pregnant and breastfeeding women in sub-Saharan Africa is critical to inform HIV prevention strategies during these periods.

methodsHIV-uninfected women presenting for antenatal care in western Kenya were enrolled and followed through 36 weeks postpartum. Sexual behavior and vaginal practices were ascertained by structured questionnaires. Logistic regression was used to assess correlates of unprotected sex, vaginal washing, and vaginal drying.

resultsAmong 1252 women enrolled, 78.4% were married (of whom 15.1% were in polygamous unions), 1.4% had a known HIV-infected partner, and 33.6% had a partner of unknown HIV status. At enrollment, 58.5% reported sex in the past month (94.3% unprotected) and 4.5% reported forced sex. Odds of unprotected sex at enrollment was >11-fold higher in married than in unmarried women (P < 0.001) and lower among women who reported partners of unknown HIV status or HIV-infected compared with HIV-uninfected partners. Median time to postpartum resumption of sex was 7 weeks (interquartile range 4-12). Prevalence of unprotected sex in the past week increased from 6.6% to 60.0% between 2 and 36 weeks postpartum (P < 0.001). Vaginal washing was reported by 60.1% of women at enrollment and prevalence remained stable postpartum; vaginal drying was reported by 17.9% at enrollment and decreased to 6.1% at 36 weeks postpartum (P < 0.001). Vaginal washing and drying were associated with forced sex.

conclusionsHigh rates of unknown partner HIV status, polygamy, and less frequent condom use among pregnant/postpartum women underscore the need for female-controlled HIV prevention interventions. Vaginal washing and drying may present challenges to microbicide use.

Indexed as

HygienePostpartum PeriodPregnancySexual BehaviorFemaleHIV InfectionsHumansKenyaProspective StudiesSurveys and QuestionnairesVaginaYoung Adult

Identifiers

PMID27828872
PMCPMC5357239
OpenAlexW2555638569

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.