Evidence map›Paper›PMID 27828635›Full record

ReviewAnais brasileiros de dermatologia

Wound healing - A literature review.

Ana Cristina de Oliveira Gonzalez, Tila Fortuna Costa, Zilton de Araújo Andrade, Alena Ribeiro Alves Peixoto Medrado

Abstract readReview
In one paragraph

Review in Anais brasileiros de dermatologia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 568 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
568citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

568 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Trial
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  7. Study on the effect and mechanism of Yanghe decoction Huacai on tissue repair ofsyndrome after anal fistula surgery.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan · 2024
    Trial
  8. Trial
  9. Pharmaceutical biology · 2026
    Article
  10. Article
  11. Article
  12. Dual-Component Nanoemulsion ContainingPlants (Basel, Switzerland) · 2026
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

508 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ana Cristina de Oliveira GonzalezFundação Oswaldo Cruz (Fiocruz), Salvador, BA, Brazil.
Tila Fortuna CostaBahiana School of Medicine and Public Health (EBMSP), Salvador, BA, Brazil.
Zilton de Araújo AndradeFundação Oswaldo Cruz (Fiocruz), Salvador, BA, Brazil.
Alena Ribeiro Alves Peixoto MedradoBahiana School of Medicine and Public Health (EBMSP), Salvador, BA, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Regeneration and tissue repair processes consist of a sequence of molecular and cellular events which occur after the onset of a tissue lesion in order to restore the damaged tissue. The exsudative, proliferative, and extracellular matrix remodeling phases are sequential events that occur through the integration of dynamic processes involving soluble mediators, blood cells, and parenchymal cells. Exsudative phenomena that take place after injury contribute to the development of tissue edema. The proliferative stage seeks to reduce the area of tissue injury by contracting myofibroblasts and fibroplasia. At this stage, angiogenesis and reepithelialization processes can still be observed. Endothelial cells are able to differentiate into mesenchymal components, and this difference appears to be finely orchestrated by a set of signaling proteins that have been studied in the literature. This pathway is known as Hedgehog. The purpose of this review is to describe the various cellular and molecular aspects involved in the skin healing process.

Indexed as

Cell ProliferationCollagenEpithelial-Mesenchymal TransitionHedgehog ProteinsHumansNeovascularization, PhysiologicRe-EpithelializationWound HealingCollagenHedgehog Proteins

Identifiers

PMID27828635
PMCPMC5087220

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.