Evidence map›Paper›PMID 27828609›Full record

ArticleCadernos de saude publica2016

Mind the gap: implementation challenges break the link between HIV/AIDS research and practice.

Sarah MacCarthy, Sari Reisner, Michael Hoffmann, Amaya Perez-Brumer, Alfonso Silva-Santisteban, Amy Nunn, Leonardo Bastos, Mauricio Teixeira Leite de Vasconcellos, Ligia Kerr, Francisco Inácio Bastos and 1 more

Abstract read
In one paragraph

Article in Cadernos de saude publica, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sarah MacCarthyRAND Corporation, Santa Monica, U.S.A.
Sari ReisnerHarvard School of Public Health, Harvard University, Boston, U.S.A.
Michael HoffmannSchool of Public Health, Brown University, Providence, U.S.A.
Amaya Perez-BrumerMailman School of Public Health, Columbia University, New York, U.S.A.
Alfonso Silva-SantistebanUniversidad Peruana Cayetano Heredia, Lima, Perú.
Amy NunnSchool of Public Health, Brown University, Providence, U.S.A.
Leonardo BastosPrograma de Computação Científica, Fundação Oswaldo Cruz, Rio de Janeiro, Brasil.
Mauricio Teixeira Leite de VasconcellosEscola Nacional de Ciências Estatísticas, Fundação Instituto Brasileiro de Geografia e Estatística, Rio de Janeiro, Brasil.
Ligia KerrFaculdade de Medicina, Universidade Federal da Ceará, Fortaleza, Brasil.
Francisco Inácio BastosInstituto de Comunicação e Informação Científica e Tecnológica em Saúde, Fundação Oswaldo Cruz, Rio de Janeiro, Brasil.
Inês DouradoInstituto de Saúde Coletiva, Universidade Federal da Bahia, Salvador, Brasil.

Funding

Translational ScienceP30AI042853 · NIAID · MIRIAM HOSPITAL · PI LARRY K BROWN · 1998 to 2026
$51.7M
HIV and Other Infectious Consequences of Substance UseT32DA013911 · NIDA · MIRIAM HOSPITAL · PI TRACI C GREEN, JOSIAH D RICH · 2001 to 2026
$9.6M
The Brown Initiative in HIV and AIDS Clinical Research for Minority CommunitiesR25MH083620 · NIMH · MIRIAM HOSPITAL · PI NUNN, AMY STEWART · 2008 to 2025
$3.7M
NIAID NIH HHS P30 AI042853NIDA NIH HHS T32 DA013911NIMHD NIH HHS L60 MD003501NIMH NIH HHS R25 MH083620
6 · The paper itself

Abstract

Sampling strategies such as respondent-driven sampling (RDS) and time-location sampling (TLS) offer unique opportunities to access key populations such as men who have sex with men (MSM) and transgender women. Limited work has assessed implementation challenges of these methods. Overcoming implementation challenges can improve research quality and increase uptake of HIV services among key populations. Drawing from studies using RDS in Brazil and TLS in Peru, we summarize challenges encountered in the field and potential strategies to address them. In Brazil, study site selection, cash incentives, and seed selection challenged RDS implementation with MSM. In Peru, expansive geography, safety concerns, and time required for study participation complicated TLS implementation with MSM and transgender women. Formative research, meaningful participation of key populations across stages of research, and transparency in study design are needed to link HIV/AIDS research and practice. Addressing implementation challenges can close gaps in accessing services among those most burdened by the epidemic.

Indexed as

Acquired Immunodeficiency SyndromeHomosexuality, MaleTransgender PersonsAdultBrazilCross-Sectional StudiesData CollectionFemaleHumansMalePeruSampling Studies

Identifiers

PMID27828609
PMCPMC5881890

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.