Evidence map›Paper›PMID 27827986›Full record

ArticleGenes2016

Replicated Risk Nicotinic Cholinergic Receptor Genes for Nicotine Dependence.

Lingjun Zuo, Rolando Garcia-Milian, Xiaoyun Guo, Chunlong Zhong, Yunlong Tan, Zhiren Wang, Jijun Wang, Xiaoping Wang, Longli Kang, Lu Lu and 3 more

Open access · goldAbstract read
In one paragraph

Article in Genes, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.3field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 8 institutions in 2 countries.

Lingjun ZuoDepartment of Psychiatry, Yale University School of Medicine, New Haven, CT 06510, USA. Lingjun.Zuo@yale.edu.
Rolando Garcia-MilianCurriculum & Research Support Department, Cushing/Whitney Medical Library, Yale University School of Medicine, New Haven, CT 06510, USA. Rolando.Milian@yale.edu.
Xiaoyun GuoDepartment of Psychiatry, Yale University School of Medicine, New Haven, CT 06510, USA. Xiaoyun.Guo@yale.edu.
Chunlong ZhongDepartment of Neurosurgery, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China. chunlongzhong@126.com.
Yunlong TanBiological Psychiatry Research Center, Beijing Huilongguan Hospital, Beijing 100096, China. yltan21@126.com.
Zhiren WangBiological Psychiatry Research Center, Beijing Huilongguan Hospital, Beijing 100096, China. zhiren75@163.com.
Jijun WangShanghai Mental Health Center, Shanghai 200030, China. jijunwang27@163.com.
Xiaoping WangDepartment of Neurology, Shanghai First People's Hospital, Shanghai Jiao Tong University, Shanghai 200080, China. x_p_wang@sjtu.edu.cn.
Longli KangKey Laboratory for Molecular Genetic Mechanisms and Intervention Research on High Altitude Diseases of Tibet Autonomous Region, Xizang Minzu University School of Medicine, Xianyang, Shanxi 712082, China. klonglister@gmail.com.
Lu LuProvincial Key Laboratory for Inflammation and Molecular Drug Target, Medical College of Nantong University, Nantong 226001, China. lulu@uthsc.edu.
Xiangning ChenNevada Institute of Personalized Medicine, University of Nevada, Las Vegas, NV 89154, USA. xiangning.chen@unlv.edu.
Chiang-Shan R LiDepartment of Psychiatry, Yale University School of Medicine, New Haven, CT 06510, USA. Chiang-Shan.Li@yale.edu.
Xingguang LuoDepartment of Psychiatry, Yale University School of Medicine, New Haven, CT 06510, USA. Xingguang.Luo@yale.edu.
Yale University · USBeijing HuiLongGuan Hospital · CNShanghai Jiao Tong University · CNShanghai Mental Health Center · CNUniversity of Nevada, Las Vegas · USUniversity of Tennessee Health Science Center · USWhitney Museum of American Art · USXizang Minzu University · CN

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Institutional Career Development CoreKL2TR001862 · NCATS · YALE UNIVERSITY · PI CANTLEY, LLOYD G, EDELMAN, E. JENNIFER · 2016 to 2025
$12.2M
Deep Sequencing of CNR1 Gene Network in Substance DependenceK01DA029643 · NIDA · YALE UNIVERSITY · PI ZUO, LINGJUN · 2010 to 2014
$909k
Imaging Cognitive Control in Cocaine DependenceK02DA026990 · NIDA · YALE UNIVERSITY · PI LI, CHIANG-SHAN RAY · 2009 to 2013
$639k
Sequencing of glutamatergic pathway genes in alcohol and nicotine co-dependenceR21AA020319 · NIAAA · YALE UNIVERSITY · PI ZUO, LINGJUN · 2011 to 2012
$344k
Post-GWAS transcriptome-wide LncRNA expression profiling in alcohol dependenceR21AA023237 · NIAAA · YALE UNIVERSITY · PI LUO, XINGGUANG · 2015 to 2016
$344k
Deep sequencing of genes in ethanol-metabolism pathway in alcoholismR21AA021380 · NIAAA · YALE UNIVERSITY · PI LUO, XINGGUANG · 2014 to 2015
$339k
NCATS NIH HHS KL2 TR001862NCATS NIH HHS UL1 TR001863NIAAA NIH HHS R21 AA020319NIAAA NIH HHS R21 AA021380NIAAA NIH HHS R21 AA023237NIDA NIH HHS K01 DA029643NIDA NIH HHS K02 DA026990
6 · The paper itself

Abstract

It has been hypothesized that the nicotinic acetylcholine receptors (nAChRs) play important roles in nicotine dependence (ND) and influence the number of cigarettes smoked per day (CPD) in smokers. We compiled the associations between nicotinic cholinergic receptor genes (

Indexed as

bioinformaticsCHRNnAChRnicotine dependencereplication

Identifiers

PMID27827986
PMCPMC5126781
OpenAlexW2551512398

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.