Trial reportScientific reports2016
Composition of gut microbiota in infants in China and global comparison.
Trial report in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06926166 (Human Genes and Microbiota in Early Life), which is not on this map. Cited by 43 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Human Genes and Microbiota in Early Life (HuGME)
Who cites it
43 citing papers in PubMed.
- Neonatal intensive care unit (NICU) exposures exert a sustained influence on the progression of gut microbiota and metabolome in the first year of life.Scientific reports · 2021Trial
- Trial
- Global and local trajectories of infant gut microbiota development in Bangladesh across the COVID-19 pandemic.mSystems · 2026Article
- Global analysis of infant gut microbiota revealed distinctive maturation dynamics across lifestyles.NPJ biofilms and microbiomes · 2026Article
- Distinct early gut microbiota patterns by delivery mode within 100 hours of birth.World journal of clinical pediatrics · 2026Article
- Therapeutic effect ofFrontiers in pharmacology · 2026Article
- Clinical Characteristics and Early Evolution of Neonates with Perinatal Gram-Negative Bacterial Infections.Children (Basel, Switzerland) · 2025Article
- Article
- Cesarean section and socioeconomic status are associated with Bifidobacterium abundance and intestinal physiology: observations from a cross-sectional study in formula-fed infants.BMC microbiology · 2025Article
- Fecal microbiome profiles in infants with biliary atresia versus nonbiliary atresia cholestasis: a pilot study.Clinical and experimental pediatrics · 2025Article
- Efficacy of a Ready-to-Feed Starter Liquid Infant Formula Containing 2-Fucosyllactose and Lacto-N-Neotetraose in Chinese Infants: Protocol for a Double Blind, Randomized Controlled Trial.JMIR research protocols · 2025Article
- Changes in intestinal bacterial characteristics during hospitalization in the NICU in very low birth weight infants.Italian journal of pediatrics · 2025Article
- Very preterm gut microbiota development from the first week of life to 3.5 years of age: a prospective longitudinal multicenter study.Microbiology spectrum · 2025Article
- The Impact of Complementary Feeding on Fecal Microbiota in Exclusively Breast-Fed Infants with Cystic Fibrosis (A Descriptive Study).Nutrients · 2024Observational
- Faecal microbiota and cytokine profiles of rural Cambodian infants linked to diet and diarrhoeal episodes.NPJ biofilms and microbiomes · 2024Article
- Review
- Comparison of intestinal and pharyngeal microbiota in preterm infants on the first day of life and the characteristics of pharyngeal microbiota in infants delivered by cesarean section or vaginally.Frontiers in pediatrics · 2024Article
- Disentangling the age-related manner in the associations between gut microbiome and women's health: a multi-cohort microbiome study.Gut microbes · 2023Article
- Evolution of a Pathogenic Microbiome.Journal of clinical medicine · 2023Review
- The butyrate-producing and spore-forming bacterial genusGut microbiome (Cambridge, England) · 2023Review
Corrections and comments
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Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Symbiotic gut microbiota is essential for human health, and its compositional changes have been associated with various complex disorders. However, systematic investigation of the acquisition and development of gut microbial communities during early infancy are relatively rare, particularly for infants from non-Western countries. In this study, we characterize the colonization and development of infant microbiota in healthy Chinese infants and compare the pattern with those from other countries. The fecal microbiota of 2-month-old infants was considerably more diverse than that of neonates, as indicated by higher relative abundances of Veillonella, Clostridium, Bacteroides, Lactobacillus, Collinsella and Prevotella, and reduction of Escherichia and Enterococcus. The fecal microbiota of vaginally delivered infants (both neonates and 2-month-old) had significant enrichment of Bacteroides, Parabacteroides and Megamonas, whereas cesarean delivered infants had enrichment of Prevotella, Streptococcus and Trabulsiella. By global comparison, we identify three different enterotypes, referred as "P-type", "A-type "and "F-type" which were highly abundant in Proteobacteria, Actinobacteria and Firmicutes, respectively. The three enterotypes' compositons vary geographically. All Chinese infants in our study belong to the P-type. These findings may provide novel insights into our understanding of the establishment of infant fecal bacterial communities.
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