ArticleScientific reports2016
Lack of diversity at innate immunity Toll-like receptor genes in the Critically Endangered White-winged Flufftail (Sarothrura ayresi).
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Macroimmunology: The drivers and consequences of spatial patterns in wildlife immune defence.The Journal of animal ecology · 2020Pooled it
- Genomic erosion in the assessment of species' extinction risk and recovery potential.The Journal of heredity · 2026Article
- Differences between mates at the TLR1Lb locus are associated with lower reproductive success in a long-lived seabird.Scientific reports · 2024Article
- Diversity of selected toll-like receptor genes in cheetahs (Acinonyx jubatus) and African leopards (Panthera pardus pardus).Scientific reports · 2024Article
- Leveraging an existing whole-genome resequencing population data set to characterize toll-like receptor gene diversity in a threatened bird.Molecular ecology resources · 2022Article
- TLR4 and TLR8 variability in Amazonian and West Indian manatee species from Brazil.Genetics and molecular biology · 2021Article
- Genetic drift and bottleneck do not influence diversity in Toll-like receptor genes at a small spatial scale in a Himalayan passerine.Ecology and evolution · 2020Article
- Evidence of Pathogen-Induced Immunogenetic Selection across the Large Geographic Range of a Wild Seabird.Molecular biology and evolution · 2020Article
- Relaxation of selective constraints shapes variation of toll-like receptors in a colonial waterbird, the black-headed gull.Immunogenetics · 2020Article
- Adaptive genetic diversity and evidence of population genetic structure in the endangered Sierra Madre Sparrow (Xenospiza baileyi).PloS one · 2020Article
- Genetic diversity of toll-like receptor genes in the vulnerable Chinese egret (Egretta eulophotes).PloS one · 2020Article
- Episodic positive diversifying selection on key immune system genes in major avian lineages.Genetica · 2019Article
- Immunogenetic response of the bananaquit in the face of malarial parasites.BMC evolutionary biology · 2019Article
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4 authors.
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Abstract
The White-winged Flufftail (Sarothrura ayresi) population is listed as globally Critically Endangered. White-winged Flufftails are only known to occur, with any regularity, in the high-altitude wetlands of South Africa and Ethiopia. Threats to the species include the limited number of suitable breeding sites in Ethiopia and severe habitat degradation and loss both in Ethiopia and South Africa. Toll-like receptors (TLRs) are increasingly being studied in a variety of taxa as a broader approach to determine functional genetic diversity. In this study, we confirm low genetic diversity in the innate immune regions of the White-winged Flufftail similar to that observed in other bird species that have undergone population bottlenecks. Low TLR diversity in White-winged Flufftail indicates that this species is more likely to be threatened by changes to the environment that would potentially expose the species to new diseases. Thus, conservation efforts should be directed towards maintaining pristine habitat for White-winged Flufftail in its current distribution range. To date, no studies on immunogenetic variation in White-winged Flufftail have been conducted and to our knowledge, this is the first study of TLR genetic diversity in a critically endangered species.
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