Evidence map›Paper›PMID 27827387›Full record

ArticleHeredity2017

DNA sequence diversity and the efficiency of natural selection in animal mitochondrial DNA.

J James, D Castellano, A Eyre-Walker

Abstract read
In one paragraph

Article in Heredity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
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  6. Article
  7. High intraspecies allelic diversity inbioRxiv : the preprint server for biology · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

J JamesSchool of Life Sciences, University of Sussex, Brighton, UK.
D CastellanoBioinformatics Research Centre, Aarhus University, Aarhus, Denmark.
A Eyre-WalkerSchool of Life Sciences, University of Sussex, Brighton, UK.ORCID 0000-0001-5527-8729

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Selection is expected to be more efficient in species that are more diverse because both the efficiency of natural selection and DNA sequence diversity are expected to depend upon the effective population size. We explore this relationship across a data set of 751 mammal species for which we have mitochondrial polymorphism data. We introduce a method by which we can examine the relationship between our measure of the efficiency of natural selection, the nonsynonymous relative to the synonymous nucleotide site diversity (π

Indexed as

Polymorphism, GeneticSelection, GeneticAnimalsBasal MetabolismBody SizeChiropteraComputer SimulationDNA, MitochondrialMammalsModels, GeneticPopulation DensityRodentiaSequence Analysis, DNADNA, Mitochondrial

Identifiers

PMID27827387
PMCPMC5176113

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.