Evidence map›Paper›PMID 27827367›Full record

ArticleNature communications2016

CD301b+ dendritic cells stimulate tissue-resident memory CD8+ T cells to protect against genital HSV-2.

Haina Shin, Yosuke Kumamoto, Smita Gopinath, Akiko Iwasaki

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 88 citations in OpenAlex.

  1. Article
  2. Review
  3. Origins of CD8 tissue resident memory.Frontiers in immunology · 2026
    Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Review
  12. CD8+ Tissue-Resident Memory T Cells: Versatile Guardians of the Tissue.Journal of immunology (Baltimore, Md. : 1950) · 2024
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Review

3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Haina ShinDepartment of Immunobiology, Yale University School of Medicine, New Haven, Connecticut 06520 USA.
Yosuke KumamotoDepartment of Immunobiology, Yale University School of Medicine, New Haven, Connecticut 06520 USA.
Smita GopinathDepartment of Immunobiology, Yale University School of Medicine, New Haven, Connecticut 06520 USA.ORCID 0000-0003-3672-3780
Akiko IwasakiDepartment of Immunobiology, Yale University School of Medicine, New Haven, Connecticut 06520 USA.ORCID 0000-0002-7824-9856
Yale University · USHoward Hughes Medical Institute · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Yale Pathology Tissue Services Shared ResourceP30CA016359 · NCI · YALE UNIVERSITY · PI DAVID L RIMM · 1985 to 2026
$85.0M
Immunity to Genital Herpes Simplex-2R01AI054359 · NIAID · YALE UNIVERSITY · PI IWASAKI, AKIKO · 2004 to 2019
$5.2M
Viral Recognition by plasmacytoid dendritic cellR01AI064705 · NIAID · YALE UNIVERSITY · PI IWASAKI, AKIKO · 2006 to 2015
$3.9M
Antiviral CTL mobilization to the genital mucosaR01AI062428 · NIAID · YALE UNIVERSITY · PI IWASAKI, AKIKO · 2005 to 2015
$3.9M
Autophagy in Antiviral ImmunityR01AI081884 · NIAID · YALE UNIVERSITY · PI IWASAKI, AKIKO · 2010 to 2014
$2.0M
Antiviral CTL mobilization to the genital mucosaR56AI062428 · NIAID · YALE UNIVERSITY · PI IWASAKI, AKIKO · 2010 to 2010
$403k
Memory CD8 T cell-mediated antiviral protection of the peripheral nervous systemK22AI119367 · NIAID · WASHINGTON UNIVERSITY · PI SHIN, HAINA · 2015 to 2016
$270k
NCATS NIH HHS UL1 TR001863NCI NIH HHS P30 CA016359NIAID NIH HHS K22 AI119367NIAID NIH HHS R01 AI054359NIAID NIH HHS R01 AI062428NIAID NIH HHS R01 AI064705NIAID NIH HHS R01 AI081884NIAID NIH HHS R56 AI062428
6 · The paper itself

Abstract

Tissue-resident memory CD8+ T (CD8 T

Indexed as

Adoptive TransferAnimalsCD8-Positive T-LymphocytesDendritic CellsFemaleHerpes GenitalisHerpesvirus 2, HumanImmunologic MemoryLectins, C-TypeMice, Inbred C57BLMice, KnockoutMice, TransgenicMicroscopy, FluorescenceVaginaLectins, C-TypeMGL2 protein, mouse

Identifiers

PMID27827367
PMCPMC5105190
OpenAlexW2550811433

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.