ArticleNature communications2016
Neural correlates of working memory development in adolescent primates.
Article in Nature communications, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed, 48 citations in OpenAlex.
- Trajectories of Response Inhibition Development in Adolescence.bioRxiv : the preprint server for biology · 2026Article
- Population-level encoding of task information is stronger in the adolescent compared to adult frontal cortex.Developmental cognitive neuroscience · 2026Article
- Longitudinal measures of monkey brain structure and activity through adolescence predict cognitive maturation.Nature neuroscience · 2025Article
- Development of an Automated Training Device for Macaque Monkeys.Basic and clinical neuroscience · 2025Article
- Increased frontoparietal activity related to lower performance in neuropsychological assessment of working memory.NeuroImage · 2025Article
- Parallel signatures of cognitive maturation in primate antisaccade performance and prefrontal activity.iScience · 2024Article
- Contributions of narrow- and broad-spiking prefrontal and parietal neurons on working memory tasks.Frontiers in systems neuroscience · 2024Article
- Laminar pattern of adolescent development changes in working memory neuronal activity.Journal of neurophysiology · 2023Article
- Strength of Excitatory Inputs to Layer 3 Pyramidal Neurons During Synaptic Pruning in the Monkey Prefrontal Cortex: Relevance for the Pathogenesis of Schizophrenia.Biological psychiatry · 2023Article
- Laminar pattern of adolescent development changes in working memory neuronal activity.bioRxiv : the preprint server for biology · 2023Article
- Longitudinal effects of early psychosocial deprivation on macaque executive function: Evidence from computational modelling.Proceedings. Biological sciences · 2023Article
- Using Nonhuman Primate Models to Reverse-Engineer Prefrontal Circuit Failure Underlying Cognitive Deficits in Schizophrenia.Current topics in behavioral neurosciences · 2023Review
- Pruning recurrent neural networks replicates adolescent changes in working memory and reinforcement learning.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Strong Gamma Frequency Oscillations in the Adolescent Prefrontal Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- Neural Mechanisms of Working Memory Accuracy Revealed by Recurrent Neural Networks.Frontiers in systems neuroscience · 2022Article
- Emergence of prefrontal neuron maturation properties by training recurrent neural networks in cognitive tasks.iScience · 2021Article
- Working Memory: From Neural Activity to the Sentient Mind.Comprehensive Physiology · 2021Article
- Drifts in Prefrontal and Parietal Neuronal Activity Influence Working Memory Judgments.Cerebral cortex (New York, N.Y. : 1991) · 2021Article
- Infant isoflurane exposure affects social behaviours, but does not impair specific cognitive domains in juvenile non-human primates.British journal of anaesthesia · 2021Article
- Reward-Sensitive Basal Ganglia Stabilize the Maintenance of Goal-Relevant Neural Patterns in Adolescents.Journal of cognitive neuroscience · 2020Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
Working memory ability matures after puberty, in parallel with structural changes in the prefrontal cortex, but little is known about how changes in prefrontal neuronal activity mediate this cognitive improvement in primates. To address this issue, we compare behavioural performance and neurophysiological activity in monkeys as they transitioned from puberty into adulthood. Here we report that monkeys perform working memory tasks reliably during puberty and show modest improvement in adulthood. The adult prefrontal cortex is characterized by increased activity during the delay period of the task but no change in the representation of stimuli. Activity evoked by distracting stimuli also decreases in the adult prefrontal cortex. The increase in delay period activity relative to the baseline activity of prefrontal neurons is the best correlate of maturation and is not merely a consequence of improved performance. Our results reveal neural correlates of the working memory improvement typical of primate adolescence.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.