Evidence map›Paper›PMID 27827316›Full record

Trial reportClinical cancer research : an official journal of the American Association for Cancer Research2017

BRM Promoter Polymorphisms and Survival of Advanced Non-Small Cell Lung Cancer Patients in the Princess Margaret Cohort and CCTG BR.24 Trial.

Geoffrey Liu, Sinead Cuffe, Shermi Liang, Abul Kalam Azad, Lu Cheng, Yonathan Brhane, Xin Qiu, David W Cescon, Jeffrey Bruce, Zhuo Chen and 14 more

Open access · bronzeAbstract readClinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Clinical cancer research : an official journal of the American Association for Cancer Research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. The role of SMARCA4 in lung cancer.Scientific reports · 2025
    Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 1 institution in 1 country.

Geoffrey LiuPrincess Margaret Cancer Centre and University Health Network, University of Toronto, Toronto, Ontario, Canada. geoffrey.liu@uhn.ca.
Sinead CuffePrincess Margaret Cancer Centre and University Health Network, University of Toronto, Toronto, Ontario, Canada.
Shermi LiangUniversity of Florida, Gainesville, Florida.
Abul Kalam AzadPrincess Margaret Cancer Centre and University Health Network, University of Toronto, Toronto, Ontario, Canada.
Lu ChengPrincess Margaret Cancer Centre and University Health Network, University of Toronto, Toronto, Ontario, Canada.
Yonathan BrhanePrincess Margaret Cancer Centre and University Health Network, University of Toronto, Toronto, Ontario, Canada.
Xin QiuPrincess Margaret Cancer Centre and University Health Network, University of Toronto, Toronto, Ontario, Canada.
David W CesconPrincess Margaret Cancer Centre and University Health Network, University of Toronto, Toronto, Ontario, Canada.
Jeffrey BrucePrincess Margaret Cancer Centre and University Health Network, University of Toronto, Toronto, Ontario, Canada.
Zhuo ChenPrincess Margaret Cancer Centre and University Health Network, University of Toronto, Toronto, Ontario, Canada.
Dangxiao ChengPrincess Margaret Cancer Centre and University Health Network, University of Toronto, Toronto, Ontario, Canada.
Devalben PatelPrincess Margaret Cancer Centre and University Health Network, University of Toronto, Toronto, Ontario, Canada.
Brandon C TsePrincess Margaret Cancer Centre and University Health Network, University of Toronto, Toronto, Ontario, Canada.
Scott A LaurieOttawa Hospital Cancer Centre, Ottawa, Ontario, Canada.
Glenwood GossOttawa Hospital Cancer Centre, Ottawa, Ontario, Canada.
Natasha B LeighlPrincess Margaret Cancer Centre and University Health Network, University of Toronto, Toronto, Ontario, Canada.
Rayjean HungLunenfeld Research Institute and Mount Sinai Hospital, Toronto, Ontario, Canada.
Penelope A BradburyPrincess Margaret Cancer Centre and University Health Network, University of Toronto, Toronto, Ontario, Canada.
Lesley SeymourCanadian Cancer Trials Group, Queens University, Kingston, Ontario, Canada.
Frances A ShepherdPrincess Margaret Cancer Centre and University Health Network, University of Toronto, Toronto, Ontario, Canada.
Ming Sound TsaoPrincess Margaret Cancer Centre and University Health Network, University of Toronto, Toronto, Ontario, Canada.
Bingshu E ChenCanadian Cancer Trials Group, Queens University, Kingston, Ontario, Canada.
Wei XuPrincess Margaret Cancer Centre and University Health Network, University of Toronto, Toronto, Ontario, Canada.
David N ReismanUniversity of Florida, Gainesville, Florida.
Ontario Institute for Cancer Research · CA

Funding

Impact of BRG1 Loss in Lung Cancer DevelopmentR01CA127636 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI REISMAN, DAVID N · 2007 to 2012
$1.4M
Identifying Agents which Restored BRM expressionR01CA136683 · NCI · UNIVERSITY OF FLORIDA · PI REISMAN, DAVID N · 2010 to 2013
$877k
Alterations of the Human SWI/SNF Complex in Lung CancerK08CA092149 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI REISMAN, DAVID N · 2002 to 2006
$689k
Establishing BRM Polymorphisms as Predictive Biomarkers for Lung Cancer RiskR41CA162414 · NCI · ZENAGENE, INC. · PI REISMAN, DAVID N · 2013 to 2013
$178k
BRM promoter polymorphism, a marker for cancer risksR03CA128038 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI REISMAN, DAVID N · 2008 to 2009
$151k
NCI NIH HHS K08 CA092149NCI NIH HHS L30 CA103750NCI NIH HHS R01 CA127636NCI NIH HHS R01 CA136683NCI NIH HHS R03 CA128038NCI NIH HHS R41 CA162414
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Genetic Predisposition to DiseaseAdultAgedAged, 80 and overCarcinoma, Non-Small-Cell LungChromatin Assembly and DisassemblyChromosomal Proteins, Non-HistoneDisease-Free SurvivalFemaleGene Expression Regulation, NeoplasticHistone DeacetylasesHomozygoteHumansMaleMEF2 Transcription FactorsMiddle AgedChromosomal Proteins, Non-HistoneHDAC9 protein, humanHistone DeacetylasesMEF2D protein, humanMEF2 Transcription FactorsRepressor ProteinsSMARCA2 protein, humanSWI-SNF-B chromatin-remodeling complexTranscription Factors

Identifiers

PMID27827316
PMCPMC5422138
OpenAlexW2550395684

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.