Evidence map›Paper›PMID 27826950›Full record

ArticleEJNMMI research2016

Effects of common anesthetic agents on [

Mikael Palner, Corinne Beinat, Sam Banister, Francesca Zanderigo, Jun Hyung Park, Bin Shen, Trine Hjoernevik, Jae Ho Jung, Byung Chul Lee, Sang Eun Kim and 2 more

Open access · goldAbstract read
In one paragraph

Article in EJNMMI research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. GABAMolecular imaging and biology · 2020
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 4 countries.

Mikael PalnerDepartments of Radiology, Stanford University School of Medicine, Stanford, CA, USA. mikael.palner@nru.dk.
Corinne BeinatDepartments of Radiology, Stanford University School of Medicine, Stanford, CA, USA.
Sam BanisterDepartments of Radiology, Stanford University School of Medicine, Stanford, CA, USA.
Francesca ZanderigoDepartment of Molecular Imaging and Neuropathology, New York State Psychiatric Institute, New York, NY, USA.
Jun Hyung ParkDepartments of Radiology, Stanford University School of Medicine, Stanford, CA, USA.
Bin ShenDepartments of Radiology, Stanford University School of Medicine, Stanford, CA, USA.
Trine HjoernevikDepartments of Radiology, Stanford University School of Medicine, Stanford, CA, USA.
Jae Ho JungBio Imaging Korea Co., Ltd, Seoul, Republic of Korea.
Byung Chul LeeDepartment of Nuclear Medicine, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.
Sang Eun KimDepartment of Nuclear Medicine, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.
Lawrence FungPsychiatry & Behavioral Sciences, Stanford University School of Medicine, Stanford, CA, USA.
Frederick T ChinDepartments of Radiology, Stanford University School of Medicine, Stanford, CA, USA. chinf@stanford.edu.
Stanford University · USSeoul National University Bundang Hospital · KRBio-Medical Science (South Korea) · KRNew York Psychoanalytic Society and Institute · US

Funding

Cross-Species Multi-Modal Neuroimaging to Investigate GABA Physiology in Fragile X SyndromeR01HD084214 · NICHD · STANFORD UNIVERSITY · PI CHIN, FREDERICK T · 2014 to 2018
$2.7M
Small animal PET system for molecular imaging of rodents and primatesS10OD018130 · OD · STANFORD UNIVERSITY · PI CHIN, FREDERICK T · 2014 to 2014
$600k
NICHD NIH HHS R01 HD084214NIH HHS S10 OD018130
6 · The paper itself

Abstract

backgroundThe availability of GABA

methodsBrain and whole blood radioactivity concentrations were measured ex vivo by scintillation counting or in vivo by PET in four groups of mice following administration of [

resultsPET images showed persistence of high [

conclusionsAnesthesia has pronounced effects on the binding and blood-brain distribution of [

Indexed as

AnesthesiaDexmedetomidineFlumazenilGABAA receptorIsofluraneKetaminePET

Identifiers

PMID27826950
PMCPMC5101239
OpenAlexW2550266034

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.