Evidence map›Paper›PMID 27826897›Full record

ArticleThe journal of physiological sciences : JPS2017

Interactions between β-adrenergic vasodilation and cervical sympathetic nerves are mediated by α

Hisayoshi Ishii, Toshiya Sato

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in The journal of physiological sciences : JPS, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Hisayoshi IshiiDivision of Physiology, Department of Oral Biology, School of Dentistry, Health Sciences University of Hokkaido, 1757 Kanazawa, Ishikari-Tobetsu, Hokkaido, 061-0293, Japan. hisayosh@hoku-iryo-u.ac.jp.ORCID http://orcid.org/0000-0002-0622-5257
Toshiya SatoDivision of Physiology, Department of Oral Biology, School of Dentistry, Health Sciences University of Hokkaido, 1757 Kanazawa, Ishikari-Tobetsu, Hokkaido, 061-0293, Japan.
Health Sciences University of Hokkaido · JP

Funding

MEXT KAKENHI 25462896
6 · The paper itself

Abstract

Neural and humoral autonomic mechanisms may be important in the maintenance of blood flow in the masseter muscle (MBF). However, their interactions remain unclear. In this study, we examined interactions between neural and humoral regulation of MBF and investigated the mechanisms mediating these interactions in urethane-anesthetized rats. Stimulation of the adrenal nerve (AN) projecting to the adrenal medulla increased MBF, and this increase was mediated by β-adrenoceptors. Sectioning of the superior cervical sympathetic trunk (CST) significantly inhibited increases in MBF induced by AN stimulation during high activity in the CST, but not during low activity. AN stimulation with clonidine after CST sectioning induced a significant increased in MBF, however phenylephrine had no observable effect. Pretreatment with yohimbine or propranolol significantly inhibited the increase in the MBF. Our results suggest an interaction between β-adrenergic vasodilation evoked by circulating adrenaline and the cervical sympathetic nerves that is mediated by α

Indexed as

Adrenergic alpha-2 Receptor AgonistsAdrenergic alpha-2 Receptor AntagonistsAnimalsClonidineElectric StimulationLipMaleMasseter MuscleMydriaticsNorepinephrinePhenylephrinePropranololRatsRats, WistarReceptors, Adrenergic, alpha-2VasodilationAdrenergic alpha-2 Receptor AgonistsAdrenergic alpha-2 Receptor AntagonistsClonidineMydriaticsNorepinephrinePhenylephrinePropranololReceptors, Adrenergic, alpha-2Vasodilator AgentsYohimbineAdrenal nerveCervical sympathetic toneCirculating adrenalineMasseter muscle blood flowα-Adrenoceptors

Identifiers

PMID27826897
PMCPMC5910521
OpenAlexW2557216013

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.