Evidence map›Paper›PMID 27826877›Full record

ArticleBulletin of mathematical biology2017

Antimicrobial Stewardship and Environmental Decontamination for the Control of Clostridium difficile Transmission in Healthcare Settings.

Jason Bintz, Suzanne Lenhart, Cristina Lanzas

Abstract read
In one paragraph

Article in Bulletin of mathematical biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jason BintzDepartment of Mathematics, Houghton College, Houghton, NY, 14744, USA.
Suzanne LenhartDepartment of Mathematics, University of Tennessee, Knoxville, TN, 37996, USA. lenhart@math.utk.edu.ORCID 0000-0002-6898-5796
Cristina LanzasDepartment of Population Health and Pathobiology, North Carolina State University, Raleigh, NC, 27607, USA.

Funding

Modeling and control of environmentally transmitted pathogensR01GM113239 · NIGMS · UNIVERSITY OF TENNESSEE KNOXVILLE · PI LANZAS, CRISTINA · 2014 to 2017
$624k
NIGMS NIH HHS R01 GM113239
6 · The paper itself

Abstract

We implement an agent-based model for Clostridium difficile transmission in hospitals that accounts for several processes and individual factors including environmental and antibiotic heterogeneity in order to evaluate the efficacy of various control measures aimed at reducing environmental contamination and mitigating the effects of antibiotic use on transmission. In particular, we account for local contamination levels that contribute to the probability of colonization and we account for both the number and type of antibiotic treatments given to patients. Simulations illustrate the relative efficacy of several strategies for the reduction of nosocomial colonizations and nosocomial diseases.

Indexed as

Models, BiologicalAnti-Bacterial AgentsClostridioides difficileComputer SimulationCross InfectionDecontaminationEnterocolitis, PseudomembranousEnvironmental MicrobiologyGastrointestinal MicrobiomeHumansMathematical ConceptsAnti-Bacterial AgentsAgent-based modelClostridium difficileControl

Identifiers

PMID27826877
PMCPMC5495002

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.