Evidence map›Paper›PMID 27826873›Full record

ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2017

Comparison of the impact of cancer between British and US long-term non-Hodgkin lymphoma survivors.

Shah-Jalal Sarker, Sophia K Smith, Kashfia Chowdhury, Patricia A Ganz, Sheryl Zimmerman, John Gribben, Ania Korszun

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Measuring quality of life in people living with and beyond cancer in the UK.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Shah-Jalal SarkerCentre for Experimental Cancer Medicine, Barts Cancer Institute, Queen Mary University of London, London, UK.
Sophia K SmithCancer Care Research Program, Duke Clinical Research Institute, Durham, USA.
Kashfia ChowdhuryCentre for Experimental Cancer Medicine, Barts Cancer Institute, Queen Mary University of London, London, UK.
Patricia A GanzUCLA Schools of Medicine and Public Health, Jonsson Comprehensive Cancer Center , Los Angeles, USA.
Sheryl ZimmermanSchool of Social Work, University of Illinois , Chicago, USA.
John GribbenCentre for Haemato-Oncology, Barts Cancer Institute , Queen Mary University of London, London, UK.
Ania KorszunCentre for Psychiatry, Wolfson Institute of Preventive Medicine, Queen Mary University of London,, London, UK. a.korszun@qmul.ac.uk.
Queen Mary University of London · GBClinical Research Institute · USUCLA Jonsson Comprehensive Cancer CenterUniversity of Illinois Chicago · US

Funding

Quality of Life of Older Long-term Lymphoma SurvivorsR03CA101492 · NCI · UNIVERSITY OF NORTH CAROLINA CHAPEL HILL · PI SMITH, SOPHIA K · 2004 to 2005
$142k
NCI NIH HHS R03 CA101492
6 · The paper itself

Abstract

purposeThe aims of this study were to examine quality of life, using the Impact of Cancer version 2 (IOCv2), in British non-Hodgkin lymphoma (NHL) survivors and investigate differences between survivors in the UK and the USA.

methodsNHL survivors (326 UK and 667 US) completed the 37-item IOCv2 and psychological distress, fatigue and social support questionnaires.

resultsThe IOCv2 showed good reliability in the British sample with higher internal consistency (Cronbach alpha 0.7-0.9) and no floor and ceiling effects. UK survivors showed significantly higher negative (p < 0.001) and higher positive (p = 0.003) IOC compared to US survivors. Younger survivors (p = 0.003), those with shorter time since diagnosis (p < 0.001) and with lower levels of social support (p = 0.001), showed more negative IOC in both groups. Higher negative IOC was also significantly associated with fatigue (p < 0.001) and depressive symptoms (p < 0.001) in both countries. Higher positive IOC was associated with female gender (p < 0.001), longer time since diagnosis (p = 0.02), those diagnosed at later stage (p < 0.05) and with greater social support (p = 0.004). Whereas significantly lower positive IOC was associated with white ethnicity (p < 0.001), higher education levels (p < 0.05) and fatigue (p = 0.001).

conclusionsThe IOCv2 is reliable and applicable in UK and US populations. Both negative and positive IOC scores were higher in British compared to US survivors. However, in both countries, psychosocial factors consistently showed the greatest impact on QOL irrespective of clinical characteristics. Recognition and treatment of individuals with these risk factors is a high priority for improving QOL in long-term cancer survivors, as is the development of modular interventions aimed at increasing positive IOC as well as decreasing negative impact. The IOCv2 shows great potential both as a screening and assessment measure for examining cancer-related outcomes among survivors.

Indexed as

AgedFemaleHumansLymphoma, Non-HodgkinMaleMiddle AgedPsychometricsQuality of LifeReproducibility of ResultsRisk FactorsSocial SupportSurveys and QuestionnairesSurvivorsUnited KingdomUnited StatesCancer survivorsDepressionImpact of cancer scaleNon-Hodgkin lymphomaQuality of lifeSocial support

Identifiers

PMID27826873
PMCPMC5269457
OpenAlexW2552822293

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.