Evidence map›Paper›PMID 27826545›Full record

ArticleJournal of diabetes and metabolic disorders2016

The association between bone turnover markers and microvascular complications of type 2 diabetes.

Zhila Maghbooli, Parisa Shabani, Sattar Gorgani-Firuzjaee, Arash Hossein-Nezhad

Open access · hybridAbstract read
In one paragraph

Article in Journal of diabetes and metabolic disorders, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Zhila MaghbooliEndocrinology and Metabolism Clinical Sciences Institute of Tehran University of Medical Sciences, Tehran, Iran.
Parisa ShabaniClinical Biochemistry Department, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Sattar Gorgani-FiruzjaeeDepartment of Medical Laboratory Sciences, School of Allied Health Medicine, AJA University of Medical Sciences, Tehran, Iran.
Arash Hossein-NezhadOsteoporosis Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Postal address; EMRI, 5th floor, Shariati Hospital, North Karegar Avenue, P.O Box: 1411413137, Tehran, Iran.
Tehran University of Medical Sciences · IRAja University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGlobal epidemic of diabetes is a serious health care concern because of its complications and consequently reduced life expectancy and increased morbidity. However, the bone turnover and thus bone health may be affected or even compromised by diabetes and its complications. The aim of this study was to assess whether bone turnover markers are associated with diabetes micro-vascular complications.

methodsA total of 204 type 2 diabetes patients (104 patients with diabetic micro-vascular complications (retinopathy and/or nephropathy) as a case group and 100 patients without retinopathy and/or nephropathy) as a control group were recruited in this case-control study. The biochemical and metabolic parameters and bone turnover markers were assessed in all patients.

resultsOur findings showed serum levels of osteocalcin (OC) (

conclusionsOur data suggest the possible role of PTH and BUN levels in modulating bone turnover markers in diabetic patients.

Indexed as

Bone turnover markersBUNeGFRNephropathyPTHRetinopathyType 2 Diabetes

Identifiers

PMID27826545
PMCPMC5100233
OpenAlexW2554052923

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.