Evidence map›Paper›PMID 27826542›Full record

ArticleFrontiers in cellular and infection microbiology2016

Characterization of Innate Immune Responses of Human Endothelial Cells Induced by

Meng-Hsuan Ho, Zhong-Mao Guo, Julio Chunga, J Shawn Goodwin, Hua Xie

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 39 citations in OpenAlex.

  1. Inflammation and Immune Mechanisms in Atherosclerosis.Reviews in cardiovascular medicine · 2026
    Review
  2. Effect of gut bacterial extracellular vesicles on angiogenic potential and vascular integrity: positive and negative aspects.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2026
    Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Outer membrane vesicles ofFrontiers in microbiology · 2025
    Review
  8. Review
  9. Review
  10. Review
  11. Review
  12. AmSystems · 2024
    Article
  13. Article
  14. Review
  15. Frontiers in immunology · 2023
    Review
  16. Review
  17. Implanted synthetic cells trigger tissue angiogenesis through de novo production of recombinant growth factors.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  18. Review
  19. Article
  20. Outer membrane vesicles ofFrontiers in cellular and infection microbiology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Meng-Hsuan HoOral Biology, School of Dentistry, Meharry Medical College Nashville, TN, USA.
Zhong-Mao GuoDepartment of Physiology, Meharry Medical College Nashville, TN, USA.
Julio ChungaFisk University Nashville, TN, USA.
J Shawn GoodwinDepartment of Biochemistry and Cancer Biology, Meharry Medical College Nashville, TN, USA.
Hua XieOral Biology, School of Dentistry, Meharry Medical College Nashville, TN, USA.
Meharry Medical College · USFisk University · US

Funding

Endowment for Health Disparities ResearchS21MD000104 · NIMHD · MEHARRY MEDICAL COLLEGE · PI HILDRETH, JAMES E · 2001 to 2016
$73.1M
The RCMI Program in Health Disparities Research at Meharry Medical College - SupplementU54MD007586 · NIMHD · MEHARRY MEDICAL COLLEGE · PI Maureen Sanderson · 2017 to 2026
$48.2M
VANDERBILT UNIVERSITY CTSA FOR PEDIATRIC RESEARCHUL1RR024975 · NCRR · VANDERBILT UNIVERSITY · PI BERNARD, GORDON RAPHAEL · 2007 to 2011
$45.7M
The Vanderbilt Institute for Clinical and Translational Research (VICTR)UL1TR000445 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BERNARD, GORDON RAPHAEL · 2012 to 2016
$41.4M
Technologies and Resources CoreU54MD007593 · NIMHD · MEHARRY MEDICAL COLLEGE · PI ADUNYAH, SAMUEL EVANS · 2012 to 2018
$24.7M
TrainingU54CA163072 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Tuya Pal, Karen Marie Winkfield · 2011 to 2026
$20.1M
Translational Pathology CoreU54CA163069 · NCI · MEHARRY MEDICAL COLLEGE · PI ADUNYAH, SAMUEL EVANS · 2011 to 2025
$18.8M
Meharry RCMI Program in Women's Health ResearchG12MD007586 · NIMHD · MEHARRY MEDICAL COLLEGE · PI HILDRETH, JAMES E · 2012 to 2016
$7.8M
Methamphetamine Research Program at Meharry Medical CollegeR24DA036420 · NIDA · MEHARRY MEDICAL COLLEGE · PI CHARLTON, CLIVEL G. · 2014 to 2018
$2.3M
Live Cell Imaging Confocal Microscope SystemS10RR025497 · NCRR · MEHARRY MEDICAL COLLEGE · PI GOODWIN, JEFFREY SHAWN · 2010 to 2010
$419k
Distribution correlation of P. gingivalis and S. cristatus in dental plaqueR21DE022428 · NIDCR · MEHARRY MEDICAL COLLEGE · PI XIE, HUA · 2012 to 2013
$408k
NCATS NIH HHS UL1 TR000445NCI NIH HHS U54 CA163069NCI NIH HHS U54 CA163072NCRR NIH HHS S10 RR025497NCRR NIH HHS UL1 RR024975NIDA NIH HHS R24 DA036420NIDCR NIH HHS R21 DE022428NIMHD NIH HHS G12 MD007586NIMHD NIH HHS S21 MD000104NIMHD NIH HHS U54 MD007586NIMHD NIH HHS U54 MD007593
6 · The paper itself

Abstract

Atherosclerosis, a chronic inflammatory disease of the blood vessels, is one of the most common causes of morbidity and mortality world-wide. Involvement of

Indexed as

Immunity, InnateAtherosclerosisBacterial Outer Membrane ProteinsBlood VesselsCell AdhesionCells, CulturedChemokine CXCL1Chemokine CXCL2Endothelial CellsE-SelectinGene Expression RegulationHost-Pathogen InteractionsHumansHuman Umbilical Vein Endothelial CellsInterleukin-8MonocytesBacterial Outer Membrane ProteinsChemokine CXCL1Chemokine CXCL2CXCL1 protein, humanCXCL2 protein, humanCXCL8 protein, humanE-SelectinInterleukin-8SELE protein, humanatherosclerosisE-selectinIL-8outer membrane vesiclesP. gingivalis

Identifiers

PMID27826542
PMCPMC5078693
OpenAlexW2535330569

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.