Evidence map›Paper›PMID 27826541›Full record

ArticleFrontiers in cellular and infection microbiology2016

Inhibition of H9N2 Virus Invasion into Dendritic Cells by the S-Layer Protein from

Xue Gao, Lulu Huang, Liqi Zhu, Chunxiao Mou, Qihang Hou, Qinghua Yu

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04907877 (Role of Nutritional Support With Probiotics in Adult Outpatients With Symptomatic COVID-19), which is not on this map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04907877 nacompletednot on this mapstarted 2021, after this paper: background citation

Role of Nutritional Support With Probiotics in Adult Outpatients With Symptomatic COVID-19: a Randomized Dietary Study

TypeinterventionalSponsorNordic Biotic Sp. z o.o.Ran2021 to 2023Enrolled70ConditionsCOVID-19 Respiratory InfectionArmsProbiotic, Placebo
3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 29 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Frontiers in nutrition · 2026
    Trial
  4. Review
  5. Analysis of the anti-PCV2 mechanism ofFrontiers in microbiology · 2024
    Article
  6. Review
  7. Article
  8. Review
  9. Review
  10. Frontiers in microbiology · 2022
    Article
  11. Article
  12. Cells · 2021
    Article
  13. Review
  14. Review
  15. S-Layer FromFrontiers in immunology · 2021
    Article
  16. Surface (S) Layer Proteins ofFrontiers in microbiology · 2019
    Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Xue GaoCollege of Veterinary Medicine, Histology and Embryology, Nanjing Agricultural University Nanjing, China.
Lulu HuangCollege of Veterinary Medicine, Histology and Embryology, Nanjing Agricultural University Nanjing, China.
Liqi ZhuCollege of Veterinary Medicine, Histology and Embryology, Nanjing Agricultural University Nanjing, China.
Chunxiao MouCollege of Veterinary Medicine, Histology and Embryology, Nanjing Agricultural University Nanjing, China.
Qihang HouCollege of Veterinary Medicine, Histology and Embryology, Nanjing Agricultural University Nanjing, China.
Qinghua YuCollege of Veterinary Medicine, Histology and Embryology, Nanjing Agricultural University Nanjing, China.
Nanjing Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Probiotics are essential for the prevention of virus invasion and the maintenance of the immune balance. However, the mechanism of competition between probiotics and virus are unknown. The objectives of this study were to isolate the surface layer (S-layer) protein from

Indexed as

AnimalsAntiviral AgentsCell LineCytokinesDEAD Box Protein 58Dendritic CellsDisease Models, AnimalGene ExpressionHemagglutininsInfluenza A Virus, H9N2 SubtypeInterleukin-10Lactobacillus acidophilusMembrane GlycoproteinsMiceMice, Inbred C57BLMyxovirus Resistance ProteinsAntiviral AgentsCytokinesDdx58 protein, mouseDEAD Box Protein 58G1p2 protein, mouseHemagglutininsInterleukin-10Membrane GlycoproteinsMx1 protein, mouseMyxovirus Resistance ProteinsNeuraminidaseNucleoproteinsRNA, MessengerS-layer proteinsUbiquitinsavian influenza virusdendritic cellsL. acidophilusmucosalS-layer protein

Identifiers

PMID27826541
PMCPMC5078685
OpenAlexW2534202047

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.