Evidence map›Paper›PMID 27826495›Full record

ArticleBeilstein journal of nanotechnology2016

Preparation of alginate-chitosan-cyclodextrin micro- and nanoparticles loaded with anti-tuberculosis compounds.

Albert Ivancic, Fliur Macaev, Fatma Aksakal, Veaceslav Boldescu, Serghei Pogrebnoi, Gheorghe Duca

Abstract read
In one paragraph

Article in Beilstein journal of nanotechnology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Physics, chemistry and biology of functional nanostructures III.Beilstein journal of nanotechnology · 2017
    Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Albert IvancicLaboratory of Organic Synthesis and Biopharmaceutics, Institute of Chemistry of ASM, Academiei 3, MD-2028 Chisinau, Moldova.
Fliur MacaevLaboratory of Organic Synthesis and Biopharmaceutics, Institute of Chemistry of ASM, Academiei 3, MD-2028 Chisinau, Moldova.
Fatma AksakalDepartment of Chemistry, Faculty of Science, Gebze Technical University, Kocaeli, 41400, Turkey.
Veaceslav BoldescuLaboratory of Organic Synthesis and Biopharmaceutics, Institute of Chemistry of ASM, Academiei 3, MD-2028 Chisinau, Moldova.
Serghei PogrebnoiLaboratory of Organic Synthesis and Biopharmaceutics, Institute of Chemistry of ASM, Academiei 3, MD-2028 Chisinau, Moldova.
Gheorghe DucaLaboratory of Organic Synthesis and Biopharmaceutics, Institute of Chemistry of ASM, Academiei 3, MD-2028 Chisinau, Moldova.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This paper describes the synthesis and application of alginate-chitosan-cyclodextrin micro- and nanoparticulate systems loaded with isoniazid (INH) and isoconazole nitrate (ISN) as antimycobacterial compounds. Preparation and morphology of the obtained particles, as well as antimycobacterial activity data of the obtained systems are presented. Docking of isoconazole into the active site of enoyl-acyl carrier protein reductase (InhA) of

Indexed as

chitosandensity functional theory (DFT)isoconazoleisoniazidmolecular dockingquaternary systemsodium alginateβ-cyclodextrin

Identifiers

PMID27826495
PMCPMC5082317

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.