Evidence map›Paper›PMID 27826420›Full record

ReviewMedical gas research2016

Hyperbaric oxygen preconditioning: a reliable option for neuroprotection.

Qin Hu, Anatol Manaenko, Nathanael Matei, Zhenni Guo, Ting Xu, Jiping Tang, John H Zhang

Open access · bronzeAbstract readReview
In one paragraph

Review in Medical gas research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Qin HuDepartments of Physiology and Pharmacology, Loma Linda University School of Medicine, Loma Linda, CA, USA.
Anatol ManaenkoDepartments of Physiology and Pharmacology, Loma Linda University School of Medicine, Loma Linda, CA, USA.
Nathanael MateiDepartments of Physiology and Pharmacology, Loma Linda University School of Medicine, Loma Linda, CA, USA.
Zhenni GuoDepartments of Physiology and Pharmacology, Loma Linda University School of Medicine, Loma Linda, CA, USA.
Ting XuDepartments of Physiology and Pharmacology, Loma Linda University School of Medicine, Loma Linda, CA, USA.
Jiping TangDepartments of Physiology and Pharmacology, Loma Linda University School of Medicine, Loma Linda, CA, USA.
John H ZhangDepartments of Physiology and Pharmacology, Loma Linda University School of Medicine, Loma Linda, CA, USA; Department of Neurosurgery, Loma Linda University School of Medicine, Loma Linda, CA, USA.ORCID 0000-0002-4319-4285
Loma Linda University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Brain injury is the leading cause of death and disability worldwide and clinically there is no effective therapy for neuroprotection. Hyperbaric oxygen preconditioning (HBO-PC) has been experimentally demonstrated to be neuroprotective in several models and has shown efficiency in patients undergoing on-pump coronary artery bypass graft (CABG) surgery. Compared with other preconditioning stimuli, HBO is benign and has clinically translational potential. In this review, we will summarize the results in experimental brain injury and clinical studies, elaborate the mechanisms of HBO-PC, and discuss regimes and opinions for future interventions in acute brain injury.

Indexed as

hyperbaric oxygen preconditioningischemic strokeneonatal hypoxic-ischemianeuroprotectiontraumatic brain injury

Identifiers

PMID27826420
PMCPMC5075679
OpenAlexW2402703628

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.