Evidence map›Paper›PMID 27826367›Full record

ReviewMethodist DeBakey cardiovascular journal2016

Local Inhibition of Macrophage and Smooth Muscle Cell Proliferation to Suppress Plaque Progression.

Roman A Sukhovershin, Naama E Toledano Furman, Ennio Tasciotti, Barry H Trachtenberg

Abstract readReview
In one paragraph

Review in Methodist DeBakey cardiovascular journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Mitophagy in Human Diseases.International journal of molecular sciences · 2021
    Review
  6. Mechanisms of Berberine for the Treatment of Atherosclerosis Based on Network Pharmacology.Evidence-based complementary and alternative medicine : eCAM · 2020
    Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Roman A SukhovershinHouston Methodist Research Institute, Houston, Texas.
Naama E Toledano FurmanHouston Methodist Research Institute, Houston, Texas.
Ennio TasciottiHouston Methodist Research Institute, Houston, Texas.
Barry H TrachtenbergHouston Methodist DeBakey Heart & Vascular Center, Houston Methodist Hospital, Houston, Texas.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atherosclerosis is a complex process responsible for a major burden of cardiovascular morbidity and mortality. Macrophages and smooth muscle cells (SMCs) are abundant within atherosclerotic plaques. This review discusses the role of macrophages and SMCs in plaque progression and provides an overview of nanoparticle-based approaches and other current methods for local targeting of atherosclerotic plaques.

Indexed as

AnimalsCell ProliferationDisease ProgressionHumansHydroxymethylglutaryl-CoA Reductase InhibitorsMacrophagesMuscle, Smooth, VascularPlaque, AtheroscleroticHydroxymethylglutaryl-CoA Reductase Inhibitorsatherosclerosismacrophagenanoparticlenanotechnologyplaquesmooth muscle cell

Identifiers

PMID27826367
PMCPMC5098570

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.