ReviewIranian journal of psychiatry and behavioral sciences2016
Bipolar I and II Disorders; A Systematic Review and Meta-Analysis on Differences in Comorbid Obsessive-Compulsive Disorder.
Review in Iranian journal of psychiatry and behavioral sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
14 citing papers in PubMed, 5 syntheses or guidelines pooled it, 36 citations in OpenAlex.
- Red and Processed Meat Consumption and Risk of Depression: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2020Pooled it
- Depression and Objectively Measured Physical Activity: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2020Pooled it
- Associations of mental disorders and neurotropic parasitic diseases: a meta-analysis in developing and emerging countries.BMC public health · 2019Pooled it
- Co-morbidities of mental disorders and chronic physical diseases in developing and emerging countries: a meta-analysis.BMC public health · 2019Pooled it
- Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) 2018 guidelines for the management of patients with bipolar disorder.Bipolar disorders · 2018Guideline
- Clinical practice guidelines for the management of bipolar disorder: 2025 update.Indian journal of psychiatry · 2026Article
- Childhood Clinical Features Preceding the Onset of Bipolar Versus Major Depressive Disorders During Adolescence.Journal of attention disorders · 2024Article
- Obsessive-Compulsive Disorder as an Epiphenomenon of Comorbid Bipolar Disorder? An Updated Systematic Review.Journal of clinical medicine · 2024Review
- Comparison of Aripiprazole and Risperidone effectiveness in treating obsessive-compulsive disorder in patients with bipolar disorder: Double-blind, randomized clinical trial.Health science reports · 2023Article
- Obsessive Compulsive Disorder and Bipolar Disorder Comorbidity: A Comparative Study.Iranian journal of psychiatry · 2022Article
- A breakthrough in research on depression screening: from validation to efficacy studies.Acta bio-medica : Atenei Parmensis · 2021Article
- Comorbidity of bipolar and anxiety disorders: An overview of trends in research.World journal of psychiatry · 2019Review
- Obsessive-compulsive disorder comorbid with schizophrenia and bipolar disorder.Indian journal of psychiatry · 2019Review
- Clinical management of comorbid bipolar disorder and obsessive-compulsive disorder: A case series.Acta bio-medica : Atenei Parmensis · 2018Article
Corrections and comments
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Authors and funding
6 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
contextMore than half of the bipolar disorder (BD) cases have an additional diagnosis; one of the most difficult to manage is obsessive-compulsive disorder (OCD). Although some authors recently investigated the co-occurrence of anxiety and BD, the topic remains insufficiently studied. The current study aimed to investigate differences in comorbid OCD between BD-I and BD-II. EVIDENCE ACQUISITION: A systematic review and meta-analysis was conducted on the prevalence and predictors of comorbid BD-I/BD-II and OCD. Relevant papers published until June 30, 2015 were identified searching the electronic databases MEDLINE, Embase, PsycINFO and the Cochrane Library.
resultsFourteen articles met the inclusion criteria. The pooled prevalence of BD-I in OCD was 3.9% (95% confidence interval (CI), 2.4 to 6.4, I2 = 83%, Q = 56) while that of BD-II in OCD was 13.5% (95% CI, 9.3 to 19.3, I2 = 89%, Q = 91). The pooled prevalence of OCD in BD-I was 21.7 (95% CI, 4.8 to 60.3, I2 = 84%, Q = 95). With regard to OCD-BD predictors, mean age and rate of males did not predict the prevalence of BD-I (β = 0.0731, 95% CI, -0.1097 to 0.256, z = 0.78; β = 0.035, 95% CI, -0.2356 to 0.1656, z = 0.34) and BD-II (β = 0.0577, 95% CI, -0.1942 to 0.0788, z = 0.83; β = -0.0317, 95% CI, -0.1483 to 0.085, z = 0.53) in OCD. The mean age explained some of the observed heterogeneity (R2 = 0.13; R2 = 0.08).
conclusionsThis first systematic review and meta-analysis of the prevalence and predictors of comorbid BD-I/BD-II and OCD suggests that BD-OCD comorbidity is a common condition in psychiatry. However, the available evidence does not allow to assess whether BD-I or BD-II are more common in patients with OCD.
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