Evidence map›Paper›PMID 27826319›Full record

ReviewThe journal of venomous animals and toxins including tropical diseases2016

In the picture: disulfide-poor conopeptides, a class of pharmacologically interesting compounds.

Eline K M Lebbe, Jan Tytgat

Open access · goldAbstract readReview
In one paragraph

Review in The journal of venomous animals and toxins including tropical diseases, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 52 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Characterization of anFrontiers in pharmacology · 2023
    Article
  10. Cone snail species off the Brazilian coast and their venoms: a review and update.The journal of venomous animals and toxins including tropical diseases · 2023
    Review
  11. Isolation and characterization of five novel disulfide-poor conopeptides fromThe journal of venomous animals and toxins including tropical diseases · 2022
    Article
  12. Prospecting for candidate molecules fromThe journal of venomous animals and toxins including tropical diseases · 2022
    Article
  13. Article
  14. Article
  15. In-depth transcriptome reveals the potential biotechnological application ofThe journal of venomous animals and toxins including tropical diseases · 2020
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Isolation and structural identification of a new T1-conotoxin with unique disulfide connectivities derived fromThe journal of venomous animals and toxins including tropical diseases · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Eline K M LebbeToxicology and Pharmacology, KU Leuven, O&N2, Box 922, Herestraat 49, 3000 Leuven, Belgium.
Jan TytgatToxicology and Pharmacology, KU Leuven, O&N2, Box 922, Herestraat 49, 3000 Leuven, Belgium.
KU Leuven · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During evolution, nature has embraced different strategies for species to survive. One strategy, applied by predators as diverse as snakes, scorpions, sea anemones and cone snails, is using venom to immobilize or kill a prey. This venom offers a unique and extensive source of chemical diversity as it is driven by the evolutionary pressure to improve prey capture and/or to protect their species. Cone snail venom is an example of the remarkable diversity in pharmacologically active small peptides that venoms can consist of. These venom peptides, called conopeptides, are classified into two main groups based on the number of cysteine residues, namely disulfide-rich and disulfide-poor conopeptides. Since disulfide-poor conotoxins are minor components of this venom cocktail, the number of identified peptides and the characterization of these peptides is far outclassed by its cysteine-rich equivalents. This review provides an overview of 12 families of disulfide-poor peptides identified to date as well as the state of affairs.

Indexed as

ConantokinCone snailConoCAPConoGAYConolysinConomapConomarphinCono-NPYConophanConopressinConorfamidContryphanContulakin

Identifiers

PMID27826319
PMCPMC5100318
OpenAlexW2556830682

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.