Evidence map›Paper›PMID 27826209›Full record

ArticleJournal of pain research2016

Altered homotopic connectivity in postherpetic neuralgia: a resting state fMRI study.

Jian Jiang, Lili Gu, Dan Bao, Shunda Hong, Wei He, Yonming Tan, Xianjun Zeng, Honghan Gong, Daying Zhang, Fuqing Zhou

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Article in Journal of pain research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

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22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

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3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Jian JiangDepartment of Radiology.
Lili GuDepartment of Pain, The First Affiliated Hospital, Nanchang University, Nanchang, Jiangxi, People's Republic of China.
Dan BaoDepartment of Pain, The First Affiliated Hospital, Nanchang University, Nanchang, Jiangxi, People's Republic of China.
Shunda HongDepartment of Radiology.
Wei HeDepartment of Radiology.
Yonming TanDepartment of Radiology.
Xianjun ZengDepartment of Radiology.
Honghan GongDepartment of Radiology.
Daying ZhangDepartment of Pain, The First Affiliated Hospital, Nanchang University, Nanchang, Jiangxi, People's Republic of China.
Fuqing ZhouDepartment of Radiology.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aim of this study was to explore interhemispheric intrinsic connectivity in patients with postherpetic neuralgia (PHN).

methodsWe obtained resting-state functional magnetic resonance imaging data from 18 right-handed PHN patients (11 males, 7 females; mean age, 59.67±8.41 years) and 18 well-matched healthy controls (11 males, 7 females; mean age, 38.50±7.51 years). Interhemispheric connectivity was examined using voxel-mirrored homotopic connectivity (VMHC), and seed-based functional connectivity analysis was performed.

resultsCompared with the healthy controls, the patients with PHN showed abnormally decreased homotopic connectivity in the dorsolateral prefrontal cortex and the precuneus and posterior cingulate cortex (PCUN/PCC). The decreased VMHC in the PCUN/PCC was positively correlated with the visual analog scale of PHN in the PHN patient group (

conclusionOur results indicated reduced interhemispheric functional connectivity in patients with PHN, which seems to be an important new avenue to investigate to better understand the nature of disconnection of the functional architecture in patients with PHN.

Indexed as

functional magnetic resonance imagingpainpostherpetic neuralgiaresting statevoxel-mirrored homotopic connectivity

Identifiers

PMID27826209
PMCPMC5096754

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.