Evidence map›Paper›PMID 27826197›Full record

ArticleOncoTargets and therapy2016

Elevated HABP1 protein expression correlates with progression and poor survival in patients with gastric cancer.

Hongyu Gao, Qiang Yao, Xiuwen Lan, Sen Li, Junlong Wu, Guangchun Zeng, Yingwei Xue

Open access · goldAbstract read
In one paragraph

Article in OncoTargets and therapy, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
0.8field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
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  6. gC1qR: A New Target for Cancer Immunotherapy.Frontiers in immunology · 2023
    Review
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  11. HeterozygousFrontiers in oncology · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Hongyu GaoDepartment of Gastroenterologic Surgery.
Qiang YaoDepartment of Gastroenterologic Surgery.
Xiuwen LanDepartment of Gastroenterologic Surgery.
Sen LiDepartment of Gastroenterologic Surgery.
Junlong WuDepartment of Pathology, The Affiliated Tumor Hospital, Harbin Medical University, Harbin, People's Republic of China.
Guangchun ZengDepartment of Pathology, The Affiliated Tumor Hospital, Harbin Medical University, Harbin, People's Republic of China.
Yingwei XueDepartment of Gastroenterologic Surgery.
Instituto de Gastroenterología · CU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHyaluronic acid-binding protein 1 (HABP1/gC1qR/p32) has been recently implicated in oncogenesis and cancer progression in various malignancies; however, its clinical role in gastric cancer (GC) is still unclear. PATIENTS AND

methodsFirst, HABP1 expression was determined by Western blot analysis and immunohistochemistry. Then, we evaluated the expression of HABP1 and its clinical significance in tumor tissues from 181 patients with GC.

resultsExpression of HABP1 protein in GC tissues was noticeably higher than that in adjacent nonneoplastic tissues (

conclusionThese findings demonstrated that HABP1 was an indicator for GC progression and poor survival, which highlighted its potential role as a therapeutic target for GCs.

Indexed as

gastric cancerhyaluronic acid-binding protein 1overall survival rateoverexpressionprognosis

Identifiers

PMID27826197
PMCPMC5096779
OpenAlexW2546100980

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.