Evidence map›Paper›PMID 27826117›Full record

ArticleNeurotoxicology and teratology

Neonatal inhibition of Na

Ryan A Stevens, Brandon D Butler, Saurabh S Kokane, Andrew W Womack, Qing Lin

Erratum issuedAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neurotoxicology and teratology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ryan A StevensDepartment of Biology, College of Science, The University of Texas at Arlington, Arlington, TX, USA.
Brandon D ButlerDepartment of Biology, College of Science, The University of Texas at Arlington, Arlington, TX, USA.
Saurabh S KokaneDepartment of Psychology, College of Science, The University of Texas at Arlington, Arlington, TX, USA.
Andrew W WomackDepartment of Psychology, College of Science, The University of Texas at Arlington, Arlington, TX, USA.
Qing LinDepartment of Psychology, College of Science, The University of Texas at Arlington, Arlington, TX, USA. Electronic address: qilin@uta.edu.
The University of Texas at Arlington · US

Funding

Spinal Cord-Mediated Acute Neurogenic InflammationR01NS040723 · NINDS · UNIVERSITY OF TEXAS MEDICAL BR GALVESTON · PI LIN, QING · 2001 to 2010
$2.3M
NINDS NIH HHS R01 NS040723
6 · The paper itself

Abstract

Prolonged ketamine exposure in neonates at anesthetic doses is known to cause long-term impairments of learning and memory. A current theoretical mechanism explains this phenomenon as being neuro-excitotoxicity mediated by compensatory upregulation of N-methyl-d-aspartate receptors (NMDARs), which then initiates widespread neuroapoptosis. Additionally, the excitatory behavior of GABAergic synaptic transmission mediated by GABA

Indexed as

AnimalsAnimals, NewbornBumetanideDrug CombinationsFemaleKetamineMaleMaze LearningMemory DisordersRatsSolute Carrier Family 12, Member 2Spatial LearningBumetanideDrug CombinationsKetamineSlc12a2 protein, ratSolute Carrier Family 12, Member 2AnestheticBumetanideGABA(A)RKetamineNeurotoxicityNKCC1

Identifiers

PMID27826117
PMCPMC5367952
OpenAlexW2546933341

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.