ArticleThe Journal of allergy and clinical immunology2017
Oroscomucoid like protein 3 (ORMDL3) transgenic mice have reduced levels of sphingolipids including sphingosine-1-phosphate and ceramide.
Article in The Journal of allergy and clinical immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
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The trial behind it
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Who cites it
33 citing papers in PubMed.
- Decreased sphingolipid synthesis in children with 17q21 asthma-risk genotypes.The Journal of clinical investigation · 2020Trial
- ORMDL3 regulates NLRP3 inflammasome activation by maintaining ER-mitochondria contacts in human macrophages and dictates ulcerative colitis patient outcome.The Journal of biological chemistry · 2024Article
- Simultaneous deletion of ORMDL1 and ORMDL3 proteins disrupts immune cell homeostasis.Frontiers in immunology · 2024Article
- NJK14047 Suppression of the p38 MAPK Ameliorates OVA-Induced Allergic Asthma during Sensitization and Challenge Periods.Biomolecules & therapeutics · 2023Article
- Neutrophilia in severe asthma is reduced in Ormdl3 overexpressing mice.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2023Article
- Dietary long-chain omega 3 fatty acids modify sphingolipid metabolism to facilitate airway hyperreactivity.Scientific reports · 2022Article
- The Crosstalk between FcεRI and Sphingosine Signaling in Allergic Inflammation.International journal of molecular sciences · 2022Review
- Human Rhinovirus Infection of the Respiratory Tract Affects Sphingolipid Synthesis.American journal of respiratory cell and molecular biology · 2022Article
- Sphingolipids and Asthma.Advances in experimental medicine and biology · 2022Article
- Orosomucoid-like protein 3, rhinovirus and asthma.World journal of critical care medicine · 2021Review
- Characteristics and Mechanisms of a Sphingolipid-associated Childhood Asthma Endotype.American journal of respiratory and critical care medicine · 2021Article
- Diversity and the Splice of Life: Mapping the 17q12-21.1 Locus for Variants Associated with Early-Onset Asthma in African American Individuals.American journal of respiratory and critical care medicine · 2021Article
- Increasing Sphingolipid Synthesis Alleviates Airway Hyperreactivity.American journal of respiratory cell and molecular biology · 2020Article
- Mechanisms of non-type 2 asthma.Current opinion in immunology · 2020Review
- ORMDL3 but not neighboring 17q21 gene LRRC3C is expressed in human lungs and lung cells of asthmatics.Allergy · 2020Article
- Orosomucoid-like 3 Supports Rhinovirus Replication in Human Epithelial Cells.American journal of respiratory cell and molecular biology · 2020Article
- Untargeted metabolomic profiling identifies disease-specific signatures in food allergy and asthma.The Journal of allergy and clinical immunology · 2020Article
- Functional contribution of sphingosine-1-phosphate to airway pathology in cigarette smoke-exposed mice.British journal of pharmacology · 2020Article
- Article
- The ORMDL3 asthma susceptibility gene regulates systemic ceramide levels without altering key asthma features in mice.The Journal of allergy and clinical immunology · 2019Article
Corrections and comments
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Authors and funding
5 authors.
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Abstract
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Registered trials
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